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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
mouse, human, rat
Citations:
3
Technique(s):
immunohistochemistry: 1:100-1:250
western blot: 1:500-1:1,000
western blot: 1:500-1:1,000
Uniprot accession no.:
产品名称
Anti-DPPA5 antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~14 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
immunohistochemistry: 1:100-1:250
western blot: 1:500-1:1,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... DPPA5(340168)
mouse ... Dppa5a(434423)
rat ... Dppa5(301101)
Application
Anti-DPPA5 antibody produced in rabbit is suitable for immunohistochemistry at a working dilution of 1:100 to 1:250 and for immunoblotting at 1:500 to 1:1000.
Biochem/physiol Actions
DPPA5 is specifically and differentially expressed in human cells that have pluripotency and can be used as a marker of pluripotent stem cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
The DPPA5 (developmental pluripotency associated 5) protein is strongly expressed in primordial germ cells, and the expression is down-regulated during germ cell development.
Immunogen
synthetic peptide corresponding to residues 43-60 human DPPA5. The sequence is 85% identical in mouse and rat.
Physical form
solution in phosphate buffered saline, containing 0.02% sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
Soo-Kyoung Kim et al.
Stem cells (Dayton, Ohio), 23(4), 458-462 (2005-03-26)
Pluripotent embryonic germ cells (EGCs) can be derived from the culture of primordial germ cells (PGCs). However, there are no reports of gonocytes, following the stage of PGC development, becoming stem cell lines. To analyze the gene expression differences between
Ida M A Jentoft et al.
Cell, 186(24), 5308-5327 (2023-11-06)
Mammalian oocytes are filled with poorly understood structures called cytoplasmic lattices. First discovered in the 1960s and speculated to correspond to mammalian yolk, ribosomal arrays, or intermediate filaments, their function has remained enigmatic to date. Here, we show that cytoplasmic
Shichao Liu et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 244(4), 619-627 (2015-01-27)
Mammalian first lineage segregation generates trophectoderm (TE) and pluripotent inner cell mass (ICM), which provides an ideal model for studying the mechanisms of maintenance and loss of pluripotency. In mouse, the transcription factor OCT4 restricts to ICM and plays a
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