D4876

葡聚糖来源于肠系膜明串珠菌

Name: 葡聚糖 来源于<I>肠系膜明串珠菌</I>
Brand: SIGMA

average mol wt 150,000

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线性分子式:

(C₆H₁₀O₅)_n

化学文摘社编号:

9004-54-0

UNSPSC Code:

12352201

NACRES:

NA.25

EC Number:

232-677-5

MDL number:

MFCD00130935

主要文件

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产品名称

葡聚糖来源于肠系膜明串珠菌, average mol wt 150,000

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

biological source

bacterial (Leuconostoc mesenteroides)

form

powder

optical activity

[α]/D 199°

mol wt

average mol wt 150,000

color

white

solubility

H₂O: soluble 20 mg/mL

Quality Level

200

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Application

右旋糖酐在许多应用中用作血小板聚集剂、血浆增容剂、渗透压调节剂、稳定剂、器官分离介质、基质成分、共聚物、微载体、结合剂、粘度调节剂、抗血栓药、润滑剂和物理结构成分。右旋糖酐可用作长的亲水性间隔臂，以改善结合/结合蛋白的性能（自由活动）。右旋糖酐可衍生化用于生物传感器系统。右旋糖酐 150 可用于研究铁转运至细胞、细胞膜通透性增加和红细胞聚集。

将右旋糖酐用作长的亲水性间隔臂提高了作用于大分子的固定化蛋白质的性能。

Other Notes

为了全面了解我们针对客户研究提供的各种葡聚糖产品，建议您访问我们的碳水化合物分类页面。

Preparation Note

除了最高分子量的葡聚糖D5501（分子量范围= 500万至4,000万），其他葡聚糖都具有非常好的水溶性。 Sigma测试显示，葡聚糖在水中的溶解浓度通常超过30mg/ml。葡聚糖也易溶于DMSO、甲酰胺、乙二醇和甘油。中性-水性葡聚糖溶液可通过在110-115^oC下高压灭菌30至45分钟进行灭菌。葡聚糖在高温下可以被强酸水解。葡聚糖的末端还原性端基可在碱性溶液中氧化。

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

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Effect of different iron loads on serum and tissue biochemical parameters and liver hepcidin mRNA abundance of neonatal piglets.

Mengyun Lia et al.

Archives of animal nutrition, 65(6), 477-485 (2012-01-20)

Iron (Fe) is an essential and important trace element for animals. In order to study its metabolism and relationship with hepcidin, piglet models of Fe-deficiency and Fe-overload were established by intramuscular injection with different doses of Fe-dextran (150 mg Fe/ml)

CD36 deletion improves recovery from spinal cord injury.

Scott A Myers et al.

Experimental neurology, 256, 25-38 (2014-04-03)

CD36 is a pleiotropic receptor involved in several pathophysiological conditions, including cerebral ischemia, neurovascular dysfunction and atherosclerosis, and recent reports implicate its involvement in the endoplasmic reticulum stress response (ERSR). We hypothesized that CD36 signaling contributes to the inflammation and

Non-adsorbing macromolecules promote endothelial adhesion of erythrocytes with reduced sialic acids.

Yang Yang et al.

Biochimica et biophysica acta, 1840(1), 288-293 (2013-10-01)

Abnormal adhesion of red blood cells (RBCs) to vascular endothelium is often associated with reduced levels of sialic acids on RBC membranes and with elevated levels of pro-adhesive plasma proteins. However, the synergistic effects of these two factors on the

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

Elizabeth M Bradshaw et al.

Nature neuroscience, 16(7), 848-850 (2013-05-28)

In our functional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) risk allele was associated with greater cell surface expression of CD33 in the monocytes (t50 = 10.06, P(joint) = 1.3 × 10(-13)) of young

Cell response to PEGylated poly(dopamine) coated liposomes considering shear stress.

Boon M Teo et al.

Biochimica et biophysica acta, 1830(10), 4838-4847 (2013-07-03)

Liposomes have gained immerse attention in the field of drug delivery as carriers of therapeutic molecules. Their modification with a polymer either to make them stealth (e.g. using PEG) and/or more stable (e.g. using poly(dopamine) (PDA)) is a crucial aspect

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Pharmaceutical Research Applications of Carbohydrates and Polysaccharides

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Carbohydrates as Versatile Enablers of Advanced Drug Delivery Systems

Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.

实验方案

Dextran

Dextran polymer details: composed mainly of alpha-D-(1-6) linkages with varied branch lengths.

葡聚糖

葡聚糖是葡萄糖酐聚合物。它由大约 95% 的alpha-D-(1-6)键合组成。其余的 a (1-3) 键合构成了葡聚糖的分支。分支长度的冲突数据意味着平均分支长度小于三个葡萄糖单位。但是，其他方法表明存在大于 50 个葡萄糖单位的分支。

葡聚糖来源于肠系膜明串珠菌

average mol wt 150,000

选择尺寸

关于此项目

主要文件

属性

产品名称

SMILES string

InChI key

InChI

biological source

form

optical activity

mol wt

color

solubility

Quality Level

相关类别

说明

Application

Other Notes

Preparation Note

安全信息

存储类别

wgk

flash_point_f

flash_point_c

ppe

文件

分析证书(COA)

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葡聚糖 来源于肠系膜明串珠菌

average mol wt 150,000

选择尺寸

关于此项目

主要文件

属性

产品名称

SMILES string

InChI key

InChI

biological source

form

optical activity

mol wt

color

solubility

Quality Level

相关类别

说明

Application

Other Notes

Preparation Note

安全信息

存储类别

wgk

flash_point_f

flash_point_c

ppe

文件

分析证书(COA)

已有该产品？

同行评审论文

技术文章和实验方案

商品

实验方案

相关内容

技术服务

葡聚糖来源于肠系膜明串珠菌