D6134
D -2-脱氧葡萄糖
≥99% (GC), crystalline
别名:
2-脱氧-
登录并加购，请在购物车里查看协议价、货期和发货地。
选择规格
变更视图
关于此项目
线性分子式:
CH2OH(CHOH)3CH2CHO
化学文摘社编号:
分子量:
164.16
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-823-0
Beilstein/REAXYS Number:
1723331
MDL number:
eCl@ss:
39020601
biological source
synthetic (organic)
Quality Segment
assay
≥99% (GC)
form
crystalline
technique(s)
gas chromatography (GC): suitable
color
white
mp
146-147 °C (lit.)
solubility
H2O: soluble 330 mg/mL, clear, colorless
application(s)
advanced drug delivery
storage temp.
2-8°C
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)CC=O
InChI
1S/C6H12O5/c7-2-1-4(9)6(11)5(10)3-8/h2,4-6,8-11H,1,3H2/t4-,5-,6+/m1/s1
InChI key
VRYALKFFQXWPIH-PBXRRBTRSA-N
Application
2-Deoxy-D-glucose (2-DG) is used in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). 2-Deoxy-D-glucose is used in the development of anti-cancer strategies that involve radio- and chemosensitization and oxidative stress.
Biochem/physiol Actions
2-脱氧-D-葡萄糖（2-脱氧葡萄糖）是一种葡萄糖类似物，可通过作用于己糖激酶这一糖酵解限速步骤来抑制糖酵解。 它会被己糖激酶磷酸化为不能被磷酸葡萄糖异构酶进一步代谢的2-DG-P。 这将导致2-DG-P在细胞中的集聚以及细胞ATP的缺失。在体外，2-脱氧葡萄糖已显示出可诱导自噬、提高ROS的产生并激活AMPK。
Preparation Note
A further purification of the Grade II material by recrystallization.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Still not finding the right product?
Explore all of our products under
WGK
WGK 3
存储类别
11 - Combustible Solids
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)