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Merck
CN

D7137

二羟丙酮磷酸盐 二锂盐

≥93% dry basis (enzymatic)

别名:

1,3-二羟基-2-丙酮1-磷酸酯 二锂盐, 1-羟基-3-(膦酰氧基)-2-丙酮 二锂盐, DHAP

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关于此项目

经验公式(希尔记法):
C3H5Li2O6P
化学文摘社编号:
分子量:
181.92
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1708891
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biological source

bovine (casein)

Quality Level

assay

≥93% dry basis (enzymatic)

form

powder

impurities

~0.2 mol % D-glyceraldehyde 3-phosphate

color

white

solubility

soluble 50mg plus 1ml of H2O, clear, colorless to faintly yellow

anion traces

phosphate (PO43-): ~5 mol %

cation traces

Li: 5.5-8.0% (dry basis)

storage temp.

−20°C

SMILES string

[Li+].[Li+].OCC(=O)COP([O-])([O-])=O

InChI

1S/C3H7O6P.2Li/c4-1-3(5)2-9-10(6,7)8;;/h4H,1-2H2,(H2,6,7,8);;/q;2*+1/p-2

InChI key

QWIKESRFRWLYIA-UHFFFAOYSA-L

Application

磷酸二羟丙酮(DHAP)被用于果糖代谢、丙糖和糖化研究中。它被用于涉及三碳糖池代谢及其在生理和物理过程中作用的研究中。DHAP可用作底物以帮助鉴定、区分和表征果糖-二磷酸醛缩酶(ALDOA)和磷酸丙糖异构酶。DHAP可被用于研究细胞糖化应激。

Biochem/physiol Actions

一种参与到多种通路中的代谢中间体,包括糖酵解和卡尔文循环。
磷酸二羟丙酮(DHAP)是一种参与到多种通路中的代谢中间体,包括糖酵解、糖异生、甘油代谢、磷脂酸合成、脂肪代谢和卡尔文循环。

Preparation Note

酶制剂。

Other Notes

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

Disclaimer

与二甲基缩酮不同,在用作底物前不需要水解。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chiara Fania et al.
PloS one, 12(6), e0179280-e0179280 (2017-06-20)
In the diagnosis of Alzheimer's disease (AD) total tau (T-tau), tau phosphorylated at threonine 181 (P-tau181), and the 42 amino acid isoform of alpha β-amyloid (Aβ) are well established surrogate CSF markers. However, there is a constant need for new
Daisuke Takagi et al.
Plant & cell physiology, 55(2), 333-340 (2014-01-11)
Sugar-derived reactive carbonyls (RCs), including methylglyoxal (MG), are aggressive by-products of oxidative stress known to impair the functions of multiple proteins. These advanced glycation end-products accumulate in patients with diabetes mellitus and cause major complications, including arteriosclerosis and cardiac insufficiency.
Xi Luo et al.
Scientific reports, 7(1), 15170-15170 (2017-11-11)
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry has been widely used for biomolecular analysis. However, with conventional MALDI, it is difficult to analyse low-molecular-weight compounds because of the interference of matrix ion signals. Here, we report a matrix-free on-chip pulse-heating desorption/ionization
Saheem Ahmad et al.
PloS one, 8(9), e72128-e72128 (2013-09-12)
Non-enzymatic glycation is the addition of free carbonyl group of reducing sugar to the free amino groups of proteins, resulting in the formation of a Schiff base and an Amadori product. Dihydroxyacetone (DHA) is one of the carbonyl species which
Nasser M Al-Daghri et al.
Scientific reports, 7(1), 12633-12633 (2017-10-05)
Obesity is a pathological condition caused by genetic and environmental factors, including vitamin D deficiency, which increases the risk of developing cardiovascular disorders and diabetes. This case-control study was designed to verify whether serum profiles could be identified differentiating obese

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Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

本页面介绍了一篇有关瓦博格效应的文章,以及其如何能够在正常氧气水平下,增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明,癌细胞显示出对糖酵解的依赖性增加,以满足他们的能量需求,无论是否有充足的氧气存在。

全球贸易项目编号

货号GTIN
D7137-100MG04061833588215
D7137-25MG04061833588222
D7137-250MG04061832389165
D7137-10MG04061832389158
D7137-5MG04061832389189

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