D7946
DIM-C-pPhOCH3
≥98% (HPLC)
别名:
1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane; 3,3′-[(4-Methoxyphenyl)methylene]bis-1H-indole
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选择尺寸
关于此项目
经验公式（希尔记法）:
C24H20N2O
化学文摘社编号:
分子量:
352.43
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C24H20N2O/c1-27-17-12-10-16(11-13-17)24(20-14-25-22-8-4-2-6-18(20)22)21-15-26-23-9-5-3-7-19(21)23/h2-15,24-26H,1H3
SMILES string
COc1ccc(cc1)C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45
InChI key
ZCCMKJAXOIFTHH-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
off-white to light yellow
solubility
DMSO: ≥30 mg/mL
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
DIM-C-pPhOCH3 is a Nerve Growth Factor-Induced Bα (NGFI-Bα, Nur77) agonist
Features and Benefits
This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Katriana A Popichak et al.
Molecular pharmacology, 94(4), 1174-1186 (2018-08-17)
Inflammatory activation of glial cells promotes loss of dopaminergic neurons in Parkinson disease. The transcription factor nuclear factor κB (NF-κB) regulates the expression of multiple neuroinflammatory cytokines and chemokines in activated glial cells that are damaging to neurons. Thus, inhibition
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