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E2129

伊文思蓝

Name: 伊文思蓝
Brand: SIGMA

Dye content ≥75 %, Powder

别名:

Direct Blue 53

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关于此项目

经验公式（希尔记法）:

C₃₄H₂₄N₆Na₄O₁₄S₄

化学文摘社编号:

314-13-6

分子量:

960.81

NACRES:

NA.47

PubChem Substance ID:

24894456

UNSPSC Code:

12171500

EC Number:

206-242-5

MDL number:

MFCD00004021

Colour Index Number:

23860

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产品名称

伊文思蓝, Dye content ≥75 %

form

powder

Quality Level

200

composition

Dye content, ≥75%

technique(s)

titration: suitable

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[Na+].[Na+].Cc1cc(ccc1\N=N\c2ccc3c(cc(c(N)c3c2O)S([O-])(=O)=O)S([O-])(=O)=O)-c4ccc(\N=N\c5ccc6c(cc(c(N)c6c5O)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c4

InChI

1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;

InChI key

ATNOAWAQFYGAOY-GPTZEZBUSA-J

Gene Information

human ... PTPN1(5770), PTPRF(5792)

General description

伊文思蓝（EB）C.I.23860是一种合成双偶氮染料，也称为T-1824和直接蓝53。水溶性较高的EB染料对血清白蛋白具有很强的亲和力，是一种高分子量蛋白质示踪剂。

Application

伊文思蓝是一种著名的重要染色剂，适用于组织学和荧光显微镜。伊文思蓝已用于检查细胞活力和研究血脑屏障(BBB)的渗透性。其他应用包括展示特定的垂体细胞类型、中性粒细胞质膜的选择性染色以及在荧光显微镜中作为一种猝灭剂抑制不必要的自体荧光。

Biochem/physiol Actions

伊文思蓝是一种非渗透染料。在质膜存在损伤时，染料可进入细胞质和核中并将它们染成蓝色。伊文思蓝可用于检查细胞的活力。它还可用于研究BBB（血脑屏障）的通透性。染料与白蛋白结合，从而表明BBB已分解为蛋白。

pictograms

GHS08

signalword

Danger

hcodes

H350

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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全球贸易项目编号

货号	GTIN
E2129-50G	04061835347612
E2129-100G	04061835347599
E2129-10G	04061835347605

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