E6375
Estriol 3-sulfate sodium salt
≥98% (TLC)
别名:
1,3,5(10)-Estratriene-3,16α,17β-triol 3-sulfate, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene 3-sulfate
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关于此项目
线性分子式:
C18H23O6SNa
化学文摘社编号:
分子量:
390.43
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Form:
powder
Assay:
≥98% (TLC)
InChI
1S/C18H24O6S.Na.H/c1-18-7-6-13-12-5-3-11(24-25(21,22)23)8-10(12)2-4-14(13)15(18)9-16(19)17(18)20;;/h3,5,8,13-17,19-20H,2,4,6-7,9H2,1H3,(H,21,22,23);;/t13-,14-,15+,16-,17+,18+;;/m1../s1
SMILES string
[Na].[H][C@]12CC[C@]3(C)[C@@H](O)[C@H](O)C[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24
InChI key
NGMCHEUPKPRHNC-XZEIGEQDSA-N
assay
≥98% (TLC)
form
powder
contains
~30% methylglucamine as stabilizer
solubility
methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
application(s)
diagnostic assay manufacturing
hematology
histology
shipped in
ambient
storage temp.
room temp
Quality Level
Packaging
Package size based on steroid content
U Raju et al.
Journal of steroid biochemistry, 20(4B), 1061-1065 (1984-04-01)
Although cystic lesions of the breast are not precancerous per se, statistical studies have indicated that this condition predisposes a 2- to 4-fold greater risk for breast cancer. Seeking a hormonal etiology to this correlation, investigators have analyzed breast cyst
N Tagawa et al.
Biological & pharmaceutical bulletin, 21(11), 1211-1214 (1998-12-16)
A method to prevent co-elution of steroid sulfates with proteins in serum from the pre-column in column-switching HPLC was developed. The pre-column, a polymer-coated mixed function column, was used for ion-pair chromatography with 5 mM tetra-n-butylammonium (TBA) ion. As steroid
U Raju et al.
Steroids, 50(4-6), 559-574 (1987-10-01)
The concentration of 16 alpha-hydroxydehydroepiandrosterone-3-sulfate (16 alpha-OHDHAS) was determined in 29 samples of human breast cyst fluid (BCF) and in 15 of these, androst-5-ene-3 beta,16 alpha,17 beta-triol-3-sulfate (A-TriolS) was also assayed. The median value of both was about 100 ng/mL
M Numazawa et al.
Steroids, 38(5), 557-565 (1981-11-01)
A novel synthesis of sodium 17-oxo-16 alpha-hydroxy-1,3,5(10)-estratrien-3-yl sulfate (4), sodium 16 alpha, 16 beta-dihydroxy-1,3,5(10)-estratrien-3-yl sulfate (5) and sodium 16-oxo-17 beta-hydroxy-1,3,5(10)-estratrien-3-yl sulfate (6) is described. 16 alpha-Bromo-3-hydroxy-1,3,5(10)-estratrien-17-one (1) was efficiently synthesized in one step with 70-97% yield by bromination of 3-hydroxy-1,3,5(10)-estratrien-17-one
N Shimura et al.
Nuclear medicine and biology, 22(5), 547-553 (1995-07-01)
We tried to put the estrogen metabolite to use in tumor imaging. The antibody against estriol 3-sulfate (E3 3-S), which was one of the major metabolites of estrogen in hormone-dependent mammary carcinoma, was prepared and the tissue distribution and imaging
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