E6375
Estriol 3-sulfate sodium salt
≥98% (TLC)
别名:
1,3,5(10)-Estratriene-3,16α,17β-triol 3-sulfate, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene 3-sulfate
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关于此项目
线性分子式:
C18H23O6SNa
化学文摘社编号:
分子量:
390.43
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Form:
powder
Assay:
≥98% (TLC)
InChI
1S/C18H24O6S.Na.H/c1-18-7-6-13-12-5-3-11(24-25(21,22)23)8-10(12)2-4-14(13)15(18)9-16(19)17(18)20;;/h3,5,8,13-17,19-20H,2,4,6-7,9H2,1H3,(H,21,22,23);;/t13-,14-,15+,16-,17+,18+;;/m1../s1
SMILES string
[Na].[H][C@]12CC[C@]3(C)[C@@H](O)[C@H](O)C[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24
InChI key
NGMCHEUPKPRHNC-XZEIGEQDSA-N
assay
≥98% (TLC)
form
powder
contains
~30% methylglucamine as stabilizer
solubility
methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
application(s)
diagnostic assay manufacturing
hematology
histology
shipped in
ambient
storage temp.
room temp
Quality Level
Packaging
Package size based on steroid content
T Tanaka et al.
Steroids, 46(1), 649-657 (1985-07-01)
A highly specific anti-estriol 3-sulfate antiserum was treated with 50% ammonium sulfate, and the crude globulin fraction was coupled to CNBr-activated Sepharose-4B. Addition of 0.1M Tris-HC1 buffer (pH 8.3) containing 0.1M glutamine to the solution of antigen-antibody enabled assaying without
T Tanaka et al.
Steroids, 63(10), 516-522 (1998-11-04)
A facile and sensitive chemiluminescence enzyme-linked immunosorbent assay (ELISA) of estriol 3-sulfate using a bridge-heterologous system was established. 6 alpha-Hydroxyestriol 3-sulfate 6-hemisuccinate was synthesized as a novel hapten. Antisera were raised in male guinea-pigs against 6 alpha-hydroxyestriol 3-sulfate 6-hemisuccinate-bovine serum
M Levitz et al.
Journal of steroid biochemistry, 20(4B), 971-974 (1984-04-01)
Estriol (E3), the most abundant estrogen in pregnancy is produced predominantly in the placenta from androgen precursors of fetal origin. The estriol so formed is secreted efficiently into the maternal circulation where it is converted to 4 conjugates--estriol-3-sulfate (E3-3S), estriol-16-glucosiduronate
Estriol-3-sulfate in human breast cyst fluid. Concentrations, possible origin, and physiologic implications.
U Raju et al.
Annals of the New York Academy of Sciences, 586, 83-87 (1990-01-01)
T Tanaka et al.
Steroids, 43(3), 235-242 (1984-03-01)
Antisera were raised in male guinea pigs against 6-oxoestriol 3-sulfate O-carboxymethyloxime-bovine serum albumin (BSA) conjugate. The antisera to this antigen exhibited high affinity (Ka=4.7 X 10(9)M-1) and excellent specificity for estriol 3-sulfate, showing slight cross-reactions (less than 0.43%) with other
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