方案
>95%
表单
powder
分子量
~800,000 Da
颜色
orange
溶解性
H2O: soluble 1 mg/mL
储存温度
2-8°C
应用
荧光素透明质酸已用于透明质酸 (ha) 和葡聚糖表面涂层膜 和图案化表面的荧光成像。在共聚焦荧光显微镜中也用于定位胶原/HA 复合凝胶中的透明质酸。
生化/生理作用
利用与荧光素胺偶联的透明质酸大分子 (HA) 通过荧光相关光谱法 (FCS) 通过测量荧光素标记的 HA 片段的猝灭来筛选透明质酸酶活性。它结合在源自人肿瘤的恶性间皮瘤的细胞表面上。
用于与人类肿瘤来源的恶性间皮瘤细胞表面结合。
其他说明
来自鸡冠或通过发酵。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Cancer research, 54(16), 4516-4523 (1994-08-15)
Hyaluronan-binding sites were demonstrated on the cell surface of three malignant mesothelioma cell lines derived from human tumors using either [3H]hyaluronan or fluorescein-tagged hyaluronan. No hyaluronan-binding activity was observed on normal human mesothelial cells. The absence of hyaluronan receptors on
Hyaluronan and dextran modified tubes resist cellular activation with blood contact
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Colloids and Surfaces. B, Biointerfaces, 108, 44-51 (2013)
Human macrophage adhesion on polysaccharide patterned surfaces
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Soft Matter, 7(7), 3599-3606 (2011)
Rheology and confocal reflectance microscopy as probes of mechanical properties and structure during collagen and collagen/hyaluronan self-assembly
Yang Yl and Kaufman LJ
Biophysical Journal, 96(4), 1566-1585 (2009)
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