产品名称
抗-Flotillin 1 兔抗, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~48 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
indirect immunofluorescence: 5-10 μg/mL using human HEK-293K cells
western blot: 0.5-1 μg/mL using whole extract of mouse lung
western blot: 1-2 μg/mL using whole extract of rat lung
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FLOT1(10211)
mouse ... Flot1(14251)
rat ... Flot1(64665)
Application
兔抗-脂筏标记蛋白 1 抗体可用于免疫印迹分析。
抗脂筏标记蛋白 1 抗体可用于免疫荧光和蛋白质印迹。
Biochem/physiol Actions
Flotillin 1（(FLOT1）在胞吞作用中起一定作用。它也在生长因子信号传导中起作用，并激活丝裂原活化蛋白激酶信号传导。此外，它还参与吞噬作用以及肌动蛋白细胞骨架和膜转运的调节。该蛋白还与肿瘤进展有关，在许多癌症（包括乳腺癌）中表达。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Flotillin 1（FLOT1）也称为reggie-2，是一种雌激素反应性基因，位于人类染色体6p21.33。该基因编码整合膜蛋白和脂筏的成分。
Flotillin 是脂筏（lipid raft）相关蛋白，主要在脂肪组织、条纹肌肉组织和肺中表达。 它在多种细胞过程（如吞噬、胞吞、胰岛素信号传导和神经元再生）中起关键作用。抗flotillin 1 抗体可用于免疫印迹和免疫定位。兔抗flotillin 1抗体与大鼠、小鼠和人的flotillin 1 发生特异反应。
脂筏标记蛋白 1 编码与小窝相关的完整膜蛋白。小窝是内在细胞膜上的小区域，参与囊泡运输和信号转导。
Immunogen
对应于小鼠脂筏标记蛋白 1 的氨基酸残基 413-428 的合成肽，N-端添加了半胱氨酸，与 KLH 偶联。与大鼠中的相应序列相同，与人的相应序列相差 1 个氨基酸。
Physical form
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 3
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
Brett Nixon et al.
Journal of cellular physiology, 226(10), 2651-2665 (2011-07-28)
Mammalian spermatozoa attain the ability to fertilize an oocyte as they negotiate the female reproductive tract. This acquisition of functional competence is preceded by an intricate cascade of biochemical and functional changes collectively known as "capacitation." Among the universal correlates
Jessica Y Idowu et al.
International journal of molecular sciences, 23(15) (2022-08-13)
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or
Aubin Moutal et al.
Pain, 162(1), 243-252 (2020-10-04)
Global spread of severe acute respiratory syndrome coronavirus 2 continues unabated. Binding of severe acute respiratory syndrome coronavirus 2's spike protein to host angiotensin-converting enzyme 2 triggers viral entry, but other proteins may participate, including the neuropilin-1 receptor (NRP-1). Because
Carsten Frühbeis et al.
Journal of extracellular vesicles, 4, 28239-28239 (2015-07-05)
Cells secrete extracellular vesicles (EVs) by default and in response to diverse stimuli for the purpose of cell communication and tissue homeostasis. EVs are present in all body fluids including peripheral blood, and their appearance correlates with specific physiological and
Aubin Moutal et al.
bioRxiv : the preprint server for biology (2020-09-02)
Global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues unabated. Binding of SARS-CoV-2's Spike protein to host angiotensin converting enzyme 2 triggers viral entry, but other proteins may participate, including neuropilin-1 receptor (NRP-1). As both Spike protein and
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持