F2756
荧光素二(β-D-吡喃半乳糖苷)
别名:
FDG
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关于此项目
经验公式（希尔记法）:
C32H32O15
CAS Number:
分子量:
656.59
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NC.07
方案
≥98% (HPLC)
质量水平
表单
powder
溶解性
methanol: 20 mg/mL, clear, yellow
储存温度
−20°C
SMILES字符串
OC[C@H]1O[C@@H](Oc2ccc3c(Oc4cc(O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5O)ccc4C36OC(=O)c7ccccc67)c2)[C@H](O)[C@@H](O)[C@H]1O
InChI
1S/C32H32O15/c33-11-21-23(35)25(37)27(39)30(45-21)42-13-5-7-17-19(9-13)44-20-10-14(43-31-28(40)26(38)24(36)22(12-34)46-31)6-8-18(20)32(17)16-4-2-1-3-15(16)29(41)47-32/h1-10,21-28,30-31,33-40H,11-12H2/t21-,22-,23+,24+,25+,26+,27-,28-,30-,31-/m1/s1
InChI key
ZTOBILYWTYHOJB-WBCGDKOGSA-N
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相关类别
一般描述
β-半乳糖苷酶的荧光底物
应用
荧光素二(β-D-吡喃半乳糖苷)已用作β-半乳糖苷酶试验中的底物。
荧光素二(β-D-吡喃半乳糖苷)（FDG）已可用于通过FACS（荧光激活细胞分选）检测基因表达。
生化/生理作用
荧光素二(β-D-吡喃半乳糖苷)(FDG被β-半乳糖苷酶水解成荧光素后发出荧光。它能产生与酶活性成比例的荧光。当使用β-半乳糖苷酶（Lac Z）作为报告基因时，该分子主要用于检测转染细胞中的基因表达。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: Proposal for a Novel Grading Scheme with Prognostic Significance.
David Lh Chan et al.
Theranostics, 7(5), 1149-1158 (2017-04-25)
Use of fluorescein-di-beta-D-galactopyranoside (FDG) and C12-FDG as substrates for beta-galactosidase detection by flow cytometry in animal, bacterial, and yeast cells.
Plovins A
Applied and Environmental Microbiology, 60, 4638-4638 (1994)
Tamio Furuse et al.
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Chaoqin Shen et al.
Molecular cancer, 19(1), 72-72 (2020-04-05)
Epigenetic alterations are involved in various aspects of colorectal carcinogenesis. N6-methyladenosine (m6A) modifications of RNAs are emerging as a new layer of epigenetic regulation. As the most abundant chemical modification of eukaryotic mRNA, m6A is essential for the regulation of
Alison H Clifford et al.
The Journal of rheumatology, 44(12), 1859-1866 (2017-09-17)
Large vessel uptake on positron emission tomography/computerized tomography (PET/CT) supports the diagnosis of giant cell arteritis (GCA). Its value, however, in patients without arteritis on temporal artery biopsy and in those receiving glucocorticoids remains unknown. We compared PET/CT results in
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