type
Type 70
Quality Level
form
powder
mol wt
~70,000
color
white
solubility
H2O: soluble 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
General description
Ficoll® PM70是一种高分子量支化多糖聚合物，公认不含任何离子化基团。这种蔗糖聚合物由蔗糖与环氧氯丙烷共聚形成。
Application
Ficoll® PM 70已用于：
- 用作比较研究中的大分子，评估其在玻璃化溶液中的效果
- 用作卵母细胞玻璃化过程的玻璃化溶液补充剂
- 用作人肺成纤维细胞培养的低血清培养基成分，促进形成拥挤环境
Biochem/physiol Actions
Ficoll 常用作玻璃化溶液的大分子成分。由于其密集的分支，Ficolls也可用作理想的近球形分子拥挤剂。
在细胞体积信号转导和蛋白质重折叠研究中，FicollTM PM 70用作大分子拥挤剂。这一物质可用于组织工程和大分子构象研究，开发、评估和使用大分子拥挤 (MMC) 系统和配置。 Ficoll PM-70还可用于玻璃化研究。
Legal Information
Ficoll is a registered trademark of Cytiva
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
实验方案
Ficoll 400® is a non-ionic polymer with high hydrophilicity and water solubility, suitable for various biological applications.
Ficoll 400®是由蔗糖和环氧氯丙烷共聚而成的一种高度分支化的聚合物。Ficoll 400®是完全非离子性的。由于其含有丰富的羟基，Ficoll 400®具有很强的亲水性和水溶性。
M Al-Habori
The international journal of biochemistry & cell biology, 33(9), 844-864 (2001-07-20)
Macromolecular crowding has been proposed as a mechanism by means of which a cell can sense relatively small changes in volume or, more accurately, the concentration of intracellular solutes. According to the macromolecular theory, the kinetics and equilibria of enzymes
C M Checura et al.
Theriogenology, 67(5), 919-930 (2006-12-19)
This study was designed to evaluate vitrification procedures for in vitro matured bovine oocytes for efficient blastocyst production after warming, IVF and culture. A second goal was to replace serum as the macromolecular component of the vitrification solution, without compromising
Y Georgalis et al.
Journal of colloid and interface science, 386(1), 141-147 (2012-08-23)
Ficoll PM70 is an important branched polysaccharide polymer with a variety of applications in biology and biophysics. The accepted picture for the aqueous solutions of this polymer is that of a polydisperse nearly spherical suspension with a molecular weight of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| F2878-50G | 04061842397082 |
| F2878-100G | 04061833613344 |
| F2878-250G | 04061842397075 |
| F2878-500G | 04061833613368 |