F3639
4-氟-7-氨磺酰基苯并呋喃
别名:
4-(氨磺酰)-7-氟-2,1,3-苯并恶二唑, 7-氟-2,1,3-苯并恶二唑-4-磺酰胺, 7-氟苯呋咱-4-硫氨, ABD-F
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关于此项目
经验公式（希尔记法）:
C6H4FN3O3S
化学文摘社编号:
分子量:
217.18
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5035147
InChI key
XROXHZMRDABMHS-UHFFFAOYSA-N
SMILES string
NS(=O)(=O)c1ccc(F)c2nonc12
InChI
1S/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12)
storage temp.
−20°C
Quality Level
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General description
4-氟-7-氨磺酰基苯并呋喃酯是一种荧光试剂，可无需柔性烷基链而直接连接至硫醇上的硫原子。它可用于使用高效液相色谱检测低分子硫醇。
Application
用于硫醇荧光测定的试剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
C C Chin et al.
Analytical biochemistry, 214(1), 128-134 (1993-10-01)
The use of the reagent tributyl phosphine (Bu3P) to reduce disulfides (Ruegg, U.T., and Rudinger, J., Methods Enzymol. 47, 111-116, 1977) and of 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) to block free sulphydryl groups (Toyo'oka, T., and Imai, K. Anal. Chem. 56, 2461-2464, 1984)
Y Luo et al.
The Journal of biological chemistry, 274(25), 17733-17741 (1999-06-11)
Serpins form enzymatically inactive covalent complexes (designated E*I*) with their target proteinases, corresponding most likely to the acyl enzyme that resembles the normal intermediate in substrate turnover. Formation of E*I* involves large changes in the conformation of the reactive center
S Maruta et al.
Journal of biochemistry, 128(4), 687-694 (2000-09-30)
In the presence of excess amounts of fluorine, a physiological divalent cation, magnesium (Mg(2+)), forms a novel phosphate analogue, magnesium fluoride (MgFn). Park et al. [Biochim. Biophys. Acta 1430, 127-140 (1999)] previously demonstrated that MgADP. MgFn forms a complex with
T Hiratsuka
The Journal of biological chemistry, 268(33), 24742-24750 (1993-11-25)
4-Fluoro-7-sulfamoylbenzofurazan (ABDF) has a rather small fluorophore that is linked directly to the sulfur atom of thiols without a flexible alkyl chain (Imai, K., and Toyo'oka, T. (1987) Methods Enzymol. 143, 67-75). In the present study I examined the fluorescent
Chie Moritani et al.
Biological & pharmaceutical bulletin, 40(7), 984-991 (2017-04-07)
Glutathione (GSH) is an ubiquitous thiol-containing tripeptide, which plays important roles in cellular protection from oxidative stress. In our search for a dietary source that can increase GSH levels, we discovered that a 24 h treatment of HepG2 cells with rice
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