F5251
p-Fluoro-DL-phenylalanine
≥98.0% (TLC)
别名:
4-fluoro-phenylalanine
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关于此项目
线性分子式:
FC6H4CH2CH(NH2)COOH
化学文摘社编号:
分子量:
183.18
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-113-7
MDL number:
Beilstein/REAXYS Number:
2938793
产品名称
p-Fluoro-DL-phenylalanine,
assay
≥98.0% (TLC)
Quality Segment
form
powder
color
white to off-white
mp
253-255 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
NC(Cc1ccc(F)cc1)C(O)=O
InChI
1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChI key
XWHHYOYVRVGJJY-UHFFFAOYSA-N
Biochem/physiol Actions
Inhibits mitosis and reversibly arrests HeLa cells in G2.
p-Fluoro-DL-phenylalanine (pFPhe), a toxic antimetabolite, is a racemic mixture of a substituted (halogenated) benzoyl D and L phenylalanine useful as a selection marker for wine yeast transformation and with potential use in endomorphin, antiviral, and antimicrobial drug development. Phenylalanine analogue, rho-fluorophenylalanine (pFPhe) is also used to induce apoptosis.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges