p-Fluoro-DL-phenylalanine

Name: <I>p</I>-Fluoro-<SC>DL</SC>-phenylalanine
Brand: SIGMA

≥98.0% (TLC)

别名:

4-fluoro-phenylalanine

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所有图片(1)

About This Item

线性分子式:

FC₆H₄CH₂CH(NH₂)COOH

CAS Number:

51-65-0

分子量:

183.18

Beilstein:

2938793

EC 号:

200-113-7

MDL编号:

MFCD00002600

UNSPSC代码:

12352209

eCl@ss:

32160406

PubChem化学物质编号:

24894885

NACRES:

NA.26

Product Name

p-Fluoro-DL-phenylalanine,

方案

≥98.0% (TLC)

表单

powder

颜色

white to off-white

mp

253-255 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

NC(Cc1ccc(F)cc1)C(O)=O

InChI

1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)

InChI key

XWHHYOYVRVGJJY-UHFFFAOYSA-N

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生化/生理作用

Inhibits mitosis and reversibly arrests HeLa cells in G2.

p-Fluoro-DL-phenylalanine (pFPhe), a toxic antimetabolite, is a racemic mixture of a substituted (halogenated) benzoyl D and L phenylalanine useful as a selection marker for wine yeast transformation and with potential use in endomorphin, antiviral, and antimicrobial drug development. Phenylalanine analogue, rho-fluorophenylalanine (pFPhe) is also used to induce apoptosis.