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Merck
CN

F5631

褐藻糖胶 来源于墨角藻

Crude

别名:

褐藻糖胶

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化学文摘社编号:
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
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biological source

algae (Fucus Vesiculosus)

Quality Level

form

powder

quality

Crude

color

light yellow to brown

solubility

H2O: 10 mg/mL, clear to hazy, faintly yellow to brownish-yellow

cation traces

Ca: ≤1%, Na: ≤ 8% (ICP)

storage temp.

room temp

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General description

褐藻糖胶是一种富含岩藻糖的硫酸多糖,从几种棕色海藻分离而来。

Application

来自 墨角藻 的褐藻糖胶可用作生物反应调节剂,也可作为具有广泛生物活性的潜在治疗剂。它作为一种潜在的抗癌、抗免疫和抗炎剂,可用于研究其药代动力学、安全性、有效性和给药方法。褐藻糖胶还可用于评估其组织工程应用的潜力和配方。

Biochem/physiol Actions

对褐藻糖胶的研究发现它具有广泛的生物活性,包括抗肿瘤和抗血管生成活性、免疫调节、抗炎、抗凝血、抗血栓形成和抗氧化活性。 褐藻糖胶诱导巨噬细胞活化,随后激活促分裂原活化蛋白激酶(MAPK),并导致自然杀伤细胞增殖。 褐藻糖胶作为非选择性选择素阻断剂起作用,已被证明可诱导细胞凋亡并抑制血管生成。

Preparation Note

通过修改 Black,W.a.P. 等人编写的 农业食品行业期刊第122期(1952年)第3页的方法制备。

Other Notes

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Wiktoria Blaszczak et al.
Molecules (Basel, Switzerland), 23(12) (2018-12-14)
Fucoidans have been reported to exert anticancer effects with simultaneous low toxicity against healthy tissue. That correlation was observed in several cancer models, however, it has never been investigated in head and neck cancer before. To magnify the efficacy of
Celina Maria P Guerra Dore et al.
Carbohydrate polymers, 91(1), 467-475 (2012-10-10)
Fucan (SV1) sulfated polysaccharides from the brown algae Sargassum vulgare were extracted, fractionated in acetone and examined with respect to chemical composition, anticoagulant, anti-inflammatory, antithrombotic effects and cellular proliferation. These polysaccharides contain low levels of protein, high level of carbohydrate
Suwaree Kitikiew et al.
Fish & shellfish immunology, 34(1), 280-290 (2012-12-04)
In this study, we examined the effect of fucoidan on the immune response of white shrimp Litopenaeus vannamei and its resistance against Vibrio alginolyticus infection. Fucoidan induced degranulation, caused changes in the cell morphology, and increased activation of prophenoloxidase (proPO)
Long Yu et al.
Food chemistry, 142, 197-200 (2013-09-05)
Structure of fucoidan from sea cucumber Acaudina molpadioides (Am-FUC) was investigated in this study. Low molecular weight polysaccharide of Am-FUC (Am-LMW) was prepared by enzymatic degradation and assayed by nuclear magnetic resonance. According to the structure of Am-LMW, and referring
Wei Wang et al.
Marine drugs, 10(12), 2795-2816 (2012-12-14)
Recently, the studies on the antiviral activities of marine natural products, especially marine polysaccharides, are attracting more and more attention all over the world. Marine-derived polysaccharides and their lower molecular weight oligosaccharide derivatives have been shown to possess a variety

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全球贸易项目编号

货号GTIN
F5631-1G04061826107652
F5631-500MG04061832628912

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