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Merck
CN

F8190

Sigma-Aldrich

褐藻糖胶 来源于墨角藻

≥95%

别名:

褐藻糖胶

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MDL编号:
UNSPSC代码:
12352201
NACRES:
NA.25
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生物来源

algae (Fucus Vesiculosus)

质量水平

方案

≥95%

表单

powder

颜色

light yellow

有效pH范围

5.0-11.0

溶解性

water: 10 mg/mL, clear, colorless to faintly yellow

储存温度

room temp

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一般描述

褐藻糖胶是一种富含岩藻糖的硫酸多糖,从几种棕色海藻分离而来。

应用

来自墨角藻的褐藻糖胶被用于:
  • 研究肝素红在检测褐藻糖胶中的应用
  • 研究其作为抗菌剂的生物活性
  • 研究其对晚期糖基化终产物的影响

生化/生理作用

对褐藻糖胶的研究发现它具有广泛的生物活性,包括抗肿瘤和抗血管生成活性、免疫调节、抗炎、抗凝血、抗血栓形成和抗氧化活性。 褐藻糖胶诱导巨噬细胞活化,随后激活促分裂原活化蛋白激酶(MAPK),并导致自然杀伤细胞增殖。 褐藻糖胶作为非选择性选择素阻断剂起作用,已被证明可诱导细胞凋亡并抑制血管生成。

其他说明

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jie Zhang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 130, 110534-110534 (2020-07-28)
Doxorubicin (DOX) is well-known for its potent antitumor activity but limited by its multiple and serious adverse effects. A major adverse effect is acute cardiotoxicity; yet, its mechanism has not been elucidated. Fucoidan is a multifunctional and nontoxic polysaccharide that
Xinjia He et al.
Biological & pharmaceutical bulletin, 42(3), 442-447 (2019-03-05)
Fucoidan is an active component of seaweed, and could inhibit proliferation and induce apoptotic cell death in several tumor cells. However, the function of fucoidan in breast cancer is largely unknown. In the present study, we evaluated the anti-cancer potential
Etimad Huwait et al.
Molecules (Basel, Switzerland), 27(10) (2022-05-29)
Several diseases, including atherosclerosis, are characterized by inflammation, which is initiated by leukocyte migration to the inflamed lesion. Hence, genes implicated in the early stages of inflammation are potential therapeutic targets to effectively reduce atherogenesis. Algal-derived polysaccharides are one of
Hang T T Cao et al.
Marine drugs, 16(11) (2018-11-06)
Fucoidans from brown macroalgae have beneficial biomedical properties but their use as pharma products requires homogenous oligomeric products. In this study, the action of five recombinant microbial fucoidan degrading enzymes were evaluated on fucoidans from brown macroalgae: Sargassum mcclurei, Fucus
Quantification of sulfated polysaccharides in mouse and rat plasma by the Heparin Red mix-and-read fluorescence assay
Ulrich W et al.
ARKIVOC (Gainesville, FL, United States) (2017)

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