FD2000S
异硫氰酸荧光素-葡聚糖
average mol wt 2,000,000
别名:
FITC-右旋糖酐
生物来源
synthetic (organic)
质量水平
偶联物
FITC conjugate
表单
powder
分子量
average mol wt 2,000,000
标记范围
0.003-0.020 mol FITC per mol glucose
颜色
yellow to orange
溶解性
H2O: soluble 25 mg/mL
储存温度
2-8°C
正在寻找类似产品? 访问 产品对比指南
相关类别
一般描述
葡聚糖是葡萄糖酐聚合物。 由大约95%的α-D-(166)键组成。 剩余的(163)键是葡聚糖的分支。分支长度的冲突数据意味着平均分支长度小于三个葡萄糖单位。但是，其他方法表明存在大于 50 个葡萄糖单位的分支。已发现的天然葡聚糖分子量（MW）在900万至5亿范围内。MW较低的葡聚糖分支略少，MW分布范围较窄。MW大于10,000 的葡聚糖表现得似乎它们是高度支化的。 随着MW的增加，葡聚糖分子的对称性增强。 MW为2,000至10,000的葡聚糖表现出可膨胀线圈的特性。 MW低于2,000的葡聚糖更像棒状。葡聚糖的分子量通过以下一种或多种方法测定：低角度激光散射、尺寸排阻色谱法、铜络合和蒽酮试剂、比色法还原糖测定和粘度。
应用
FITC-葡聚糖被广泛用于运用显微荧光法进行微循环和细胞通透性研究。 FITC-葡聚糖被用于植物细胞壁孔隙度和毛细血管通透性研究。研究表明，血浆蛋白不与FITC-葡聚糖结合。
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。
荧光素-葡聚糖，2000 kDa，用于使用小型集成荧光显微镜对活跃小鼠的脑微血管系统进行体内成像。FITC-葡聚糖，2000 kDa（FD-2000）在心血管、微循环、灌注和细胞膜通透性研究中用作荧光通量示踪化合物，可实现对血流、膜损伤、血管引流和肾脏清除等过程进行检测。 荧光素-葡聚糖，2000 kDa，用于使用小型集成荧光显微镜对活跃小鼠的脑微血管系统进行体内成像。 FITC-葡聚糖被用于植物细胞壁孔隙度研究。
制备说明
Sigma通常以25 mg/ml或更高的浓度测试FITC葡聚糖在水中的溶解度。 溶液应避光保存。 在体内，FITC-葡聚糖稳定24小时以上。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Baoqiang Li et al.
PloS one, 14(8), e0221547-e0221547 (2019-08-31)
Chronic atherosclerosis may cause cerebral hypoperfusion and inadequate brain oxygenation, contributing to the progression of cognitive decline. In this study, we exploited two-photon phosphorescence lifetime microscopy to measure the absolute partial pressure of oxygen (PO2) in cortical tissue in both
Weiguo Chen et al.
American journal of respiratory cell and molecular biology, 50(2), 328-336 (2013-09-14)
The statins are now recognized to have pleiotropic properties, including augmentation of endothelial barrier function. To explore the mechanisms involved, we investigated the effect of simvastatin on endothelial cell (EC) tight junctions. Western blotting of human pulmonary artery ECs treated
Haruna Hirata et al.
Biological & pharmaceutical bulletin, 37(2), 262-267 (2014-02-05)
Long-term peritoneal dialysis (PD) frequently produces morphological and functional changes of the peritoneum, which makes continuation of PD difficult. Moreover, the progression of peritoneal injury causes complications and poor prognosis. Since therapeutic treatments for peritoneal injury during PD have yet
Poornima Venkat et al.
Neurobiology of aging, 50, 96-106 (2016-12-13)
We investigated cognitive function, axonal/white matter (WM) changes and glymphatic function of vascular dementia using a multiple microinfarction (MMI) model in retired breeder (RB) rats. The MMI model induces significant (p < 0.05) cognitive decline that worsens with age starting
John Nguyen et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31(11), 2243-2254 (2011-06-30)
The accumulation of small strokes has been linked to cognitive dysfunction. Although most animal models have focused on the impact of arteriole occlusions, clinical evidence indicates that venule occlusions may also be important. We used two-photon excited fluorescence microscopy to
相关内容
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持