FD250S
异硫氰酸荧光素-葡聚糖
average mol wt 250,000
别名:
FITC-右旋糖酐
产品名称
异硫氰酸荧光素-葡聚糖, average mol wt 250,000
biological source
bacterial (Leuconostoc mesenteroides)
conjugate
FITC conjugate
form
powder
mol wt
average mol wt 250,000
extent of labeling
0.003-0.020 mol FITC per mol glucose
color
yellow to orange
solubility
water: 25 mg/mL, clear, yellow
storage temp.
2-8°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
FITC-葡聚糖在心血管、微循环、灌注、细胞单层和细胞膜通透性研究中用作荧光通量示踪化合物，可实现对血流、膜损伤、血管引流和肾脏清除等过程进行检测。 小FITC-葡聚糖也可用于检测内吞作用等过程。 FITC-葡聚糖250（FD250）可用作模型化合物，用于开发将分子递送到原生质体中和研究从水凝胶和脂质体等结构释放药物的方法。可作为研究微血管和血脑屏障的模型化合物。
FITC-葡聚糖被广泛用于运用显微荧光法进行微循环和细胞通透性研究。 FITC-葡聚糖被用于植物细胞壁孔隙度和毛细血管通透性研究。研究表明，血浆蛋白不与FITC-葡聚糖结合。
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。
General description
葡聚糖是葡萄糖酐聚合物。 由大约95%的α-D-(166)键组成。 剩余的(163)键是葡聚糖的分支。分支长度的冲突数据意味着平均分支长度小于三个葡萄糖单位。但是，其他方法表明存在大于 50 个葡萄糖单位的分支。已发现的天然葡聚糖分子量（MW）在900万至5亿范围内。MW较低的葡聚糖分支略少，MW分布范围较窄。MW大于10,000 的葡聚糖表现得似乎它们是高度支化的。 随着MW的增加，葡聚糖分子的对称性增强。 MW为2,000至10,000的葡聚糖表现出可膨胀线圈的特性。 MW低于2,000的葡聚糖更像棒状。葡聚糖的分子量通过以下一种或多种方法测定：低角度激光散射、尺寸排阻色谱法、铜络合和蒽酮试剂、比色法还原糖测定和粘度。
Preparation Note
Sigma通常以25 mg/ml或更高的浓度测试FITC葡聚糖在水中的溶解度。 溶液应避光保存。 在体内，FITC-葡聚糖稳定24小时以上。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Jennifer L Guerriero et al.
Nature, 543(7645), 428-432 (2017-03-09)
Although the main focus of immuno-oncology has been manipulating the adaptive immune system, harnessing both the innate and adaptive arms of the immune system might produce superior tumour reduction and elimination. Tumour-associated macrophages often have net pro-tumour effects, but their
Cerec Omnicam - Intraoralscan 2.0.
K Wiedhahn et al.
International journal of computerized dentistry, 15(3), 199-205 (2012-12-21)
Fabiana Gomes da Conceição et al.
Clinics (Sao Paulo, Brazil), 67(8), 923-929 (2012-09-06)
Ischemic preconditioning and some drugs can protect tissues from injury by preserving microcirculation. This study evaluated vascular permeability in a hamster cheek pouch preparation using either short ischemic periods or bradykinin as preconditioning stimuli followed by 30 min of ischemia/reperfusion.
Cristiana Marcozzi et al.
Regenerative medicine, 15(9), 2085-2098 (2020-11-18)
Aim: The proposal of this study was to evaluate, in vitro, the potential paracrine effect of human adipose-derived stem cells (hASCs) to promote lymphangiogenesis in lymphatic endothelial cells isolated from rat diaphragmatic lymphatic vessels. Materials & methods: ELISA on VEGFA, VEGFC and
Fusanori Yotsumoto et al.
Oncoimmunology, 4(4), e1001204-e1001204 (2015-07-03)
Early stage growth of intracranial B16F10 tumors is reduced by 87% in myeloid-specific NG2 null (Mac-NG2ko) mice and by 77% in pericyte-specific NG2 null (PC-NG2ko) mice, demonstrating the importance of the NG2 proteoglycan in each of these stromal compartments. In
相关内容
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持