Merck
CN
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文件

G2299

SAFC

L -氧化谷胱甘肽

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别名:
GSSG, 氧化谷胱甘肽
经验公式（希尔记法）:
C20H32N6O12S2
CAS号:
27025-41-8
分子量:
612.63
Beilstein:
1718700
EC 号:
248-170-7
MDL编号:
MFCD00063106
NACRES:
NA.21

生物来源

synthetic

质量水平

400

形式

powder

溶解性

H2O: 10 mg/mL, clear, colorless

适用性

suitable for manufacturing use

储存温度

2-8°C

SMILES字符串

N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

InChI key

YPZRWBKMTBYPTK-BJDJZHNGSA-N

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相关类别

Amino Acid Sequence

Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]

一般描述

我们的SAFC®高质量原材料产品组合用于生物制药工艺，可通过严苛的质控程序并提供配套文档和技术专长，帮助客户满足 M-Clarity 计划规定的要求。

M-Clarity 计划

我们全面的下游工艺化学品产品组合不仅为生物制药制造商提供生产传统和新型治疗制剂所需的优质原材料，还可帮助他们加速产品上市并简化监管问题。从低风险应用的非 GMP 等级，到高风险应用的 IPEC-PQG GMP标准，我们的产品可满足您的所有制造需求。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

相关产品

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Kun-Peng Wang et al.
Molecular medicine reports, 9(5), 1813-1819 (2014-03-08)
Schisandra chinensis is a well-known traditional medicinal herb. Acetaminophen is a commonly used over-the-counter analgesic and overdose of acetaminophen was the most frequent cause of acute liver failure. However, no studies have demonstrated the role of Schisandra chinensis in acetaminophen-induced
Vladimir L Kolossov et al.
Experimental biology and medicine (Maywood, N.J.), 239(4), 394-403 (2014-03-04)
The glutathione couple GSH/GSSG is the most abundant cellular redox buffer and is not at equilibrium among intracellular compartments. Perturbation of glutathione poise has been associated with tumorigenesis; however, due to analytical limitations, the underlying mechanisms behind this relationship are
Fabio Di Domenico et al.
Expert review of neurotherapeutics, 15(1), 19-40 (2014-09-23)
Alzheimer's disease (AD), characterized by progressive loss of memory, language, reasoning and other cognitive functions, including dementia, is characterized pathologically by the presence of senile plaques, neurofibrillary tangles and synapse loss. Increased oxidative/nitrosative stress, decreased antioxidants, mitochondrial damage and other
Benoît Tessoulin et al.
Blood, 124(10), 1626-1636 (2014-07-10)
The aim of this study was to assess the efficiency of p53 reactivation and induction of massive apoptosis (PRIMA-1(Met)) in inducing myeloma cell death, using 27 human myeloma cell lines (HMCLs) and 23 primary samples. Measuring the lethal dose (LD50)
Changchun Cai et al.
Hepatology (Baltimore, Md.), 60(3), 990-1002 (2014-05-07)
Acetaminophen (APAP) toxicity is the most common cause of acute liver failure in industrialized countries. Understanding the mechanisms of APAP-induced liver injury as well as other forms of sterile liver injury is critical to improve the care of patients. Recent
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