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G3295

Sigma-Aldrich

GW0742

≥98% (HPLC)

别名:

[4-[[[2-[3-氟-4-(三氟甲基)苯基]-4-甲基-5-噻唑基]甲基]硫代]-2-甲基苯氧基]乙酸

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About This Item

经验公式（希尔记法）:
C21H17F4NO3S2
CAS号:
317318-84-6
分子量:
471.49
MDL编号:
MFCD07369423
UNSPSC代码:
12352200
PubChem化学物质编号:
24895123
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white

mp

134.5-135.5 °C

溶解性

DMSO: >5 mg/mL
H2O: insoluble

创始人

GlaxoSmithKline

储存温度

2-8°C

SMILES字符串

Cc1cc(SCc2sc(nc2C)-c3ccc(c(F)c3)C(F)(F)F)ccc1OCC(O)=O

InChI

1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)

InChI key

HWVNEWGKWRGSRK-UHFFFAOYSA-N

基因信息

human ... PPARA(5465) , PPARD(5467) , PPARG(5468)

生化/生理作用

GW0742是一种高度选择性的PPARδ激动剂。 EC50 = 1 nM ，对PPARα和PPARγ的EC50分别为1 μM和2 μM。

特点和优势

该化合物在受体分类和信号转导手册的 核受体（PPAR） 页面上有详细描述。如需浏览其他手册页面，请点击此处。
该化合物由GlaxoSmithKline开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

法律信息

根据GlaxoSmithKline的协议出售用于研究目的

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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