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Merck
CN

G3882

Gly-Gly-Gly-Gly

≥98% (TLC)

别名:

Glycyl-glycyl-glycyl-glycine, Tetraglycine, Triglycyl-glycine

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关于此项目

线性分子式:
NH2CH2CO(NHCH2CO)3OH
化学文摘社编号:
分子量:
246.22
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
211-303-4
MDL number:
Beilstein/REAXYS Number:
1715387
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产品名称

Gly-Gly-Gly-Gly,

InChI key

QMOQBVOBWVNSNO-UHFFFAOYSA-N

InChI

1S/C8H14N4O5/c9-1-5(13)10-2-6(14)11-3-7(15)12-4-8(16)17/h1-4,9H2,(H,10,13)(H,11,14)(H,12,15)(H,16,17)

SMILES string

NCC(=O)NCC(=O)NCC(=O)NCC(O)=O

assay

≥98% (TLC)

form

powder

color

white to off-white

mp

300 °C

application(s)

peptide synthesis

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Tetraglycine is used with copper (Cu-II) to study mechanisms of hydrogen peroxide/bicarbonate free radical production and effect in vitro.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yanfeng Yao et al.
Emerging microbes & infections, 8(1), 45-54 (2019-03-15)
Current influenza vaccines provide hemagglutinin strain-specific protection, but rarely provide cross-protection against divergent strains. It is, therefore, particularly important to develop a universal vaccine against conserved proteins or conserved regions of the virus. In this study, we used N-terminal extracellular
Fabian Barthels et al.
ChemMedChem, 15(10), 839-850 (2020-03-03)
Staphylococcus aureus is one of the most frequent causes of nosocomial and community-acquired infections, with drug-resistant strains being responsible for tens of thousands of deaths per year. S. aureus sortase A inhibitors are designed to interfere with virulence determinants. We
Kaitlin A Doucette et al.
International journal of molecular sciences, 22(1) (2020-12-31)
The interactions of amino acids and peptides at model membrane interfaces have considerable implications for biological functions, with the ability to act as chemical messengers, hormones, neurotransmitters, and even as antibiotics and anticancer agents. In this study, glycine and the
J Ueda et al.
Biochemistry and molecular biology international, 34(4), 801-808 (1994-10-01)
At physiological pH values, Cu(II)-tetraglycine and Cu(II) complexes with peptides containing a histidyl residue at the N-terminal caused DNA strand breakage in the presence of H2O2, whereas Cu(II) complexes with peptides containing histidyl residue in the second or third position
María V Alipázaga et al.
Dalton transactions (Cambridge, England : 2003), (13)(13), 2036-2040 (2004-07-15)
The synergistic effect of Ni(II) and Co(II) on the sulfite induced autoxidation of Cu(II)/tetraglycine was investigated spectrophotometrically at 25.0 degrees C, pH = 9.0, 1 x 10(-5) mol dm(-3) < or = [S(IV)] < or = 8 x 10(-5) mol

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