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经验公式(希尔记法):
C6H11K2O9P · xH2O
化学文摘社编号:
分子量:
336.32 (anhydrous basis)
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25
产品名称
α-D-Glucose 1-phosphate dipotassium salt hydrate, ≥99% (HPLC), BioXtra
Quality Level
SMILES string
[K+].[K+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C6H13O9P.2K.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1
InChI key
VOQGDSVKCMGEFO-FBNUBEQJSA-L
biological source
synthetic
product line
BioXtra
assay
≥99% (HPLC)
form
powder
impurities
glucose and starch, essentially free
color
white to off-white
solubility
water: 50 mg/mL, clear, colorless
cation traces
K: 20.4-26.1% (ICP)
storage temp.
−20°C
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General description
α-D-Glucose 1-phosphate is the α-anomeric form of glucose which contains a phosphate group on the primary carbon. It can be converted into the deoxysugar CDP-glucose by the enzyme α-D-Glucose-1-phosphate cytidylyltransferase.
Other Notes
Formerly listed as Grade V.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Nicole M Koropatkin et al.
The Journal of biological chemistry, 279(42), 44023-44029 (2004-08-05)
Dideoxysugars, which display biological activities ranging from mediating cell-cell interactions to serving as components in some antibiotics, are synthesized in various organisms via complex biochemical pathways that begin with the attachment of alpha-D-glucose 1-phosphate to either CTP or dTTP. Here
Stanley A Blumenthal
Perspectives in biology and medicine, 55(2), 236-249 (2012-05-31)
In 1945, Earl Sutherland (1915-1974) [corrected] and associates began studies of the mechanism of hormone-induced glycogen breakdown in the liver. In 1956, their efforts culminated in the identification of cyclic AMP, an ancient molecule generated in many cell types in
Ting Yang et al.
The Biochemical journal, 429(3), 533-543 (2010-05-21)
The diverse types of glycoconjugates synthesized by trypanosomatid parasites are unique compared with the host cells. These glycans are required for the parasite survival, invasion or evasion of the host immune system. Synthesis of those glycoconjugates requires a constant supply
Bijay Singh et al.
Protein engineering, design & selection : PEDS, 25(4), 179-187 (2012-02-16)
Two similar genes, dnmL and rmbA in Streptomyces peucetius, which encode for glucose-1-phosphate (G-1-P) thymidylyltransferases were expressed in Escherichia coli under similar conditions. While RmbA was expressed in soluble form, DnmL was found as insoluble aggregates in inclusion bodies. The
Achim Dickmanns et al.
Journal of molecular biology, 405(2), 461-478 (2010-11-16)
Nucleotide sugars and the enzymes that are responsible for their synthesis are indispensable for the production of complex carbohydrates and, thus, for elaboration of a protective cellular coat for many organisms such as the protozoan parasite Leishmania. These activated sugars
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