G9753
α-D-葡萄糖胺 1-磷酸
别名:
2-Amino-2-deoxy-α-D-glucopyranosyl phosphate
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关于此项目
经验公式（希尔记法）:
C6H14NO8P
化学文摘社编号:
分子量:
259.15
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
Quality Level
InChI key
YMJBYRVFGYXULK-UHFFFAOYSA-N
SMILES string
NC1C(O)C(O)C(CO)OC1OP(O)(O)=O
InChI
1S/C6H14NO8P/c7-3-5(10)4(9)2(1-8)14-6(3)15-16(11,12)13/h2-6,8-10H,1,7H2,(H2,11,12,13)
biological source
natural (inorganic)
assay
≥97% (TLC)
form
powder
impurities
<8.5% water (Karl Fischer)
color
white
solubility
water: 100 mg/mL, clear, colorless
storage temp.
−20°C
Application
- 来自热纤梭菌（Ruminiclostridium thermocellum）的纤维糊精磷酸化酶: X-射线晶体结构和底物特异性分析。该研究介绍了利用纤维糊精磷酸化酶进行α-D-葡萄糖胺 1-磷酸类多糖的酶法合成和分析，重点介绍了其在新生物材料开发中的潜力。Field et al., 2017
- 来自梨火疫病菌（Erwinia amylovora）的葡萄糖-1-磷酸尿苷酰转移酶: 活性、结构和底物特异性。该论文探索了细菌代谢中与α-D-葡萄糖胺 1-磷酸相关的生化途径，提供了有关微生物生物化学和抗菌治疗潜在靶点的见解。Field et al., 2017
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
K Takayama et al.
The Journal of biological chemistry, 258(12), 7379-7385 (1983-06-25)
We have determined the complete structure of a glycolipid (designated lipid X) previously found to accumulate in certain Escherichia coli mutants defective in phosphatidylglycerol synthesis (Nishijima, M., and Raetz, C.R.H. (1979) J. Biol. Chem. 254, 7837-7844). Based on fast atom
F Hatzack et al.
Journal of chromatography. B, Biomedical sciences and applications, 736(1-2), 221-229 (2000-02-17)
A simple and inexpensive high-performance thin-layer chromatography (HPTLC) method for the analysis of inositol mono- to hexakisphosphates on cellulose precoated plates is described. Plates were developed in 1-propanol-25% ammonia solution-water (5:4:1) and substance quantities as low as 100-200 pmol were
Amit Parikh et al.
Journal of molecular biology, 386(2), 451-464 (2009-01-06)
Identifying direct targets of kinases and determining how their activities are regulated are central to understanding how they generate biological responses. Genetic and biochemical studies have shown that Mycobacterium tuberculosis serine/threonine protein kinases PknA and PknB play a role in
Fumitaka Kudo et al.
Journal of the American Chemical Society, 127(6), 1711-1718 (2005-02-11)
Aminoglycoside antibiotics are composed of aminosugars and a unique aminocyclitol aglycon including 2-deoxystreptamine (DOS), streptidine, actinamine, etc., and nucleotidylyltransferases, sugar modifying enzymes, and glycosyltransferases appear to be essential for their biosynthesis. However, the genes encoding those enzymes were unable to
S Ambrosio et al.
Journal of biochemical and biophysical methods, 25(4), 237-244 (1992-12-01)
Galactosamine is quickly metabolized to galactosamine 1-phosphate in rats treated with this compound. An HPLC method to quantify hexosamine phosphates in biological samples is described, modified from the o-phthaldialdehyde amino acid analysis procedure. o-Phthaldialdehyde derivatives of hexosamines and hexosamine-phosphates can
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