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Merck
CN

H0290

Hartman′s固定液

histological tissue fixative

别名:

Davidson′s固定液

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关于此项目

NACRES:
NA.47
UNSPSC Code:
12171500
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Application

用作根治性切除标本中淋巴结可视化的过夜固定剂。通过将淋巴结转变为白色,有助于乳房和结肠标本检查。Moore和Barr使用了一种Hartman固定剂来固定皮肤活检标本,用于研究细核细节。使用常规和改良的Hartman固定剂将大鼠睾丸固定24小时以用于免疫组织化学和形态学比较,而将用于其他分析的眼睛和睾丸标本固定48小时。

General description

Hartman固定剂,也称为Davidson固定剂,含有醋酸、酒精和福尔马林。它被广泛用于保存眼、骨髓、乳房、睾丸和其他组织以便组织学检查。

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3

target_organs

Central nervous system, Respiratory system

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

75.2 °F

flash_point_c

24 °C

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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John R Latendresse et al.
Toxicologic pathology, 30(4), 524-533 (2002-08-22)
Most recent revisions of regulatory guidelines for testing effects of chemicals on reproduction recommend Bouin's fluid (BF) or a "comparable fixative" instead of formalin to preserve the morphologic detail of testes for histopathological evaluation. However, picric acid in BF is
Generation and functional characterization of a conditional Pumilio2 null allele.
Lin K, et al.
Journal of biomedical research (2017)
G J Nuovo et al.
The American journal of pathology, 134(4), 837-842 (1989-04-01)
In situ hybridization is used commonly for detection of human papillomavirus (HPV) DNA. There is little information, however, on whether the detection of HPV DNA by in situ hybridization can be affected by the way in which the tissue is
The sex chromatin in human malignant tissues.
K L MOORE et al.
British journal of cancer, 11(3), 384-390 (1957-09-01)
Fixation of testes and eyes using a modified Davidson's fluid: comparison with Bouin's fluid and conventional Davidson's fluid.
Latendresse J R, et al.
Toxicologic Pathology, 30(4), 524-533 (2002)

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