H1252
高香草酸
>99% purity (TLC), powder
别名:
4-羟基-3-甲氧基苯乙酸, HVA
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关于此项目
线性分子式:
HOC6H3(OCH3)CH2CO2H
化学文摘社编号:
分子量:
182.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
206-176-7
MDL number:
Beilstein/REAXYS Number:
2213447
产品名称
高香草酸, Fluorimetric reagent
InChI key
QRMZSPFSDQBLIX-UHFFFAOYSA-N
InChI
1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)
SMILES string
COc1cc(CC(O)=O)ccc1O
assay
>99% (TLC)
form
powder
technique(s)
titration: suitable
color
white to off-white
mp
142-145 °C (lit.)
solubility
ethanol: 50 mg/mL, colorless to light yellow
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
高香草酸被用作HPLC分析的标准品。
Biochem/physiol Actions
儿茶酚O-甲基转移酶代谢二羟基苯乙酸（DOPAC）产生的代谢物；用于葡萄糖氧化酶和其他氧化酶荧光测定的试剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Tashjian AH and Armstrong EJ
Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy (2011)
Practical Fluorescence (1990)
Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease.
Tillerson JL
Neuroscience, 119, 899-899 (2003)
Forced nonuse in unilateral parkinsonian rats exacerbates injury.
Tillerson JL
The Journal of Neuroscience, 22, 6790-6790 (2002)
Michèl A Willemsen et al.
Brain : a journal of neurology, 133(Pt 6), 1810-1822 (2010-05-01)
Tyrosine hydroxylase deficiency is an autosomal recessive disorder resulting from cerebral catecholamine deficiency. Tyrosine hydroxylase deficiency has been reported in fewer than 40 patients worldwide. To recapitulate all available evidence on clinical phenotypes and rational diagnostic and therapeutic approaches for
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