H5254
橙皮苷
≥80% (HPLC)
别名:
3′,5,7-三羟基4′-甲氧基黄酮7-芸香, 橙皮素 7-鼠李糖苷, 橙皮素-7-芸香糖苷
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关于此项目
经验公式（希尔记法）:
C28H34O15
化学文摘社编号:
分子量:
610.56
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
208-288-1
Beilstein/REAXYS Number:
75140
MDL number:
产品名称
橙皮苷, ≥80% (HPLC)
InChI key
QUQPHWDTPGMPEX-QJBIFVCTSA-N
InChI
1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
SMILES string
COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2
biological source
Citrus sinensis (L.) Osbeck
assay
≥80% (HPLC)
form
powder
color
yellow to faint beige
mp
250-255 °C (dec.) (lit.)
solubility
soluble, yellow to brown
storage temp.
2-8°C
Quality Level
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Yomna S Mo'men et al.
Journal of biochemical and molecular toxicology, e22305-e22305 (2019-02-20)
Hesperidin is a flavanone glycoside that is found in the Citrus species and showed antioxidant, hepatoprotective as well as anticancer activity. This study investigated the effect of hesperidin on the PI3K/Akt pathway as a possible mechanism for its protective effect
Julia M Assini et al.
Current opinion in lipidology, 24(1), 34-40 (2012-12-21)
Citrus flavonoids are polyphenolic compounds with powerful biological properties. This review aims to summarize recent advances towards understanding the ability of citrus flavonoids to regulate lipid metabolism and other metabolic parameters relevant to the metabolic syndrome, type 2 diabetes and
Yong Yang et al.
European journal of medicinal chemistry, 58, 390-395 (2012-11-17)
We have identified a previously unknown function of the natural compound, hesperetin. Here, we demonstrate that this small molecular agent is able to inhibit the transforming growth factor-β (TGF-β) signaling pathway. Single-molecule force measurements and single-molecule fluorescence imaging show that
Leandro C Souza et al.
Progress in neuro-psychopharmacology & biological psychiatry, 40, 103-109 (2012-09-22)
The present study investigated a possible antidepressant-like activity of hesperidin using two predictive tests for antidepressant effect in mice: the forced swimming test (FST) and the tail suspension test (TST). Results demonstrated that hesperidin (0.1, 0.3 and 1 mg/kg, intraperitoneal
Binit Kumar et al.
Vascular pharmacology, 57(5-6), 201-207 (2012-09-13)
The purpose of the study was to evaluate vasculoprotective effects of Hesperetin (Hsp) in Streptozotocin induced diabetic rats. The study was carried out for a period of 24weeks and evaluated for angiogenic parameters (VEGF and PKC-β), retinal vascular leakage by
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