H6503
L-同型半胱氨酸硫内酯 盐酸盐
≥98% (TLC)
别名:
L-2-氨基-4-巯基丁酸 1,4-硫代内酯 盐酸盐
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C4H7NOS · HCl
化学文摘社编号:
分子量:
153.63
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
250-824-1
MDL number:
Beilstein/REAXYS Number:
3911455
产品名称
L-同型半胱氨酸硫内酯 盐酸盐, ≥98% (TLC)
InChI
1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
InChI key
ZSEGSUBKDDEALH-DFWYDOINSA-N
SMILES string
Cl[H].N[C@H]1CCSC1=O
assay
≥98% (TLC)
form
powder
color
white
mp
185 °C
application(s)
detection
peptide synthesis
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
- Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart：研究DL-同型半胱氨酸硫内酯对心脏功能的作用，揭示它的心血管研究用途和治疗潜力(Zivkovic et al., 2013)。
- Homocysteine is a novel risk factor for suboptimal response of blood platelets to acetylsalicylic acid in coronary artery disease：研究L-同型半胱氨酸硫内酯如何影响冠心病治疗中的血小板反应，说明它的心血管治疗意义(Karolczak et al., 2013)。
Biochem/physiol Actions
同型半胱氨酸硫代内酯是一种胺反应剂，被用于研究蛋白质翻译后修饰，尤其是赖氨酸残基的修饰。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Derrick L Sauls et al.
Thrombosis research, 127(6), 576-581 (2011-02-15)
We have shown that homocysteinemic rabbits have altered fibrinogen that forms fibrin clots with increased resistance to fibrinolysis. Homocysteine thiolactone is a metabolite of homocysteine (Hcys) that can react with amines and introduce a new sulfhydryl group into proteins. Recent
A Rašić-Marković et al.
Acta physiologica Hungarica, 98(1), 17-26 (2011-03-11)
The aim of our study was to investigate the effects of ifenprodil and MK-801 on D,L-homocysteine thiolactone induced seizures in adult rats.Male Wistar rats were divided into following groups: 1. Saline-treated (C, n=10); 2. D,L-homocysteine thiolactone 8 mmol/kg, i.p. (H
Han-Hsin Chang et al.
Molecular vision, 17, 1946-1956 (2011-08-19)
Hyperhomocysteinemia is known to cause degeneration of retinal ganglion cells, but its influence on photoreceptors remains largely unknown. In particular, the role of homocysteine-thiolactone (Hcy-T)--the physiologic metabolite of homocysteine that has been proven to be more cytotoxic than homocysteine itself--as
Hieronim Jakubowski
Acta biochimica Polonica, 58(2), 149-163 (2011-06-07)
All living organisms conduct protein synthesis with a high degree of accuracy maintained in the transmission and flow of information from a gene to protein product. One crucial 'quality control' point in maintaining a high level of accuracy is the
Homocysteine and its thiolactone-mediated modification of fibrinogen affect blood platelet adhesion.
Joanna Malinowska et al.
Platelets, 23(5), 409-412 (2011-10-21)
Homocysteine (Hcys) and homocysteine thiolactone (HTL) concentrations in organism are correlated with a number of serious pathologies. In the literature, there are few papers describing studies on the effects of homocysteine on proteins that participate in blood coagulation and fibrinolysis
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持