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Merck
CN

H7375

二磷酸组胺 一水合物

Histamine receptor ligand

别名:

2-(4-咪唑)乙胺 二磷酸盐, 4-咪唑乙胺 二磷酸盐 一水合物, 组胺 二磷酸盐 一水合物

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关于此项目

经验公式(希尔记法):
C5H9N3 · 2H3PO4 · H2O
化学文摘社编号:
分子量:
325.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
200-118-4
MDL number:
Beilstein/REAXYS Number:
3744619
Quality level:
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产品名称

二磷酸组胺 一水合物,

SMILES string

[H]O[H].OP(O)(O)=O.OP(O)(O)=O.NCCc1c[nH]cn1

InChI key

CNSGLKZGHLZDHQ-UHFFFAOYSA-N

InChI

1S/C5H9N3.2H3O4P.H2O/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4;/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4);1H2

storage temp.

−20°C

Quality Level

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Zhou, et al.
Brain sciences, 13 (2023)
R G van Wijk et al.
Allergy proceedings : the official journal of regional and state allergy societies, 14(4), 273-281 (1993-07-01)
For a study on the relationship between nasal hyperreactivity to histamine and the nasal response to allergen, 14 rhinitis patients allergic to house-dust mites were challenged with histamine and 5 days later with a house-dust mite (HDM) extract. According to
A M Majchel et al.
The Journal of allergy and clinical immunology, 90(1), 85-91 (1992-07-01)
To evaluate changes in the nasal response to histamine, we challenged 19 subjects with allergic rhinitis caused by ragweed (RW) before, during, and after the RW season with increasing doses of histamine diphosphate. We compared their response, as measured by
I K Taylor et al.
Lancet (London, England), 337(8743), 690-694 (1991-03-23)
The effects of a highly selective leukotriene D4 receptor antagonist, ICI 204.219, on allergen-induced bronchoconstriction and changes in airway reactivity were evaluated in a double-blind, placebo-controlled, crossover trial. Ten atopic subjects were selected for the study on the basis of
A M Bramley et al.
American journal of respiratory and critical care medicine, 152(5 Pt 1), 1513-1517 (1995-11-01)
The recent demonstration of increased shortening of asthmatic airway smooth muscle could result from increased contractility of the muscle itself or from a decreased load that must be overcome by the smooth muscle to shorten. To evaluate the role of

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