HPA001562
抗 ATF3 兔抗
Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
别名:
抗 环腺苷酸依赖性转录因子 ATF-3 兔抗, 抗 转录激活因子 3 兔抗
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
product line
Prestige Antibodies® Powered by Atlas Antibodies
form
buffered aqueous glycerol solution
species reactivity
human
enhanced validation
orthogonal RNAseq
Learn more about Antibody Enhanced Validation
technique(s)
immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:200-1:500
immunogen sequence
MMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTEC
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ATF3(467)
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General description
兔多克隆抗 ATF3 抗体与人活化转录因子 3 反应。
激活转录因子3（ATF3）基因定位于人染色体1q32.3。编码的蛋白属于cAMP反应元件结合（CREB）蛋白家族。
Immunogen
环腺苷酸依赖性转录因子 ATF-3 重组蛋白表位签名标签 (PrEST)
Application
兔抗ATF3抗体可用于：
- 蛋白质印迹
- 免疫荧光
- 免疫组化染色
- 染色质免疫沉淀（ChIP)
Biochem/physiol Actions
激活转录因子3（ATF3）是一种环AMP依赖性转录因子，通过隔离抑制性辅因子来刺激转录。ATF3可对胁迫信号作出响应，并参与免疫和代谢稳态的调节。它有助于防止慢性炎症和饥饿反应。眼损伤诱导ATF3表达。它可充当神经元损伤的标志物。
Features and Benefits
Prestige抗体®是经过高度表征和广泛验证的抗体，同时还有一个优点是其每个靶标的所有可用表征数据都可以通过位于此页面顶部产品名称下方的人类蛋白质图谱门户进行访问。Prestige抗体对其他蛋白质的独特性和低交叉反应性®是通过严密的抗原区域选择、亲和纯化和严格的选择来实现的。针对每一个Prestige 抗体都存在有对应的Prestige抗原对照，并可在链接区域内找到。
每个Prestige 抗体都是按照以下方法进行测试的：
每个Prestige 抗体都是按照以下方法进行测试的：
- 44例正常人类组织以及20例最常见癌症类型组织的IHC组织阵列。
- 364个人类重组蛋白片段的蛋白阵列。
Physical form
溶于磷酸盐缓冲盐水，pH 7.2，含有40%甘油和0.02%叠氮化钠
Other Notes
相应抗原APREST77475
Legal Information
Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
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Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 155(2), 172-182 (2010)
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