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Merck
CN

HT501320

甲醛溶液,中性缓冲,10%

histological tissue fixative

别名:

甲醛

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关于此项目

UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
MDL number:
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产品名称

甲醛溶液,中性缓冲,10%, histological tissue fixative

SMILES string

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

biological source

synthetic

concentration

10% formalin (approx. 4% formaldehyde)

color

colorless

pH

6.90-7.10

density

1.080 g/cm3

application(s)

hematology
histology

storage temp.

room temp

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Application

10% 中性缓冲福尔马林溶液已被用作固定组织的常用通用组织学固定剂。
常用的通用组织学固定剂。

General description

10%福尔马林中性缓冲液通常用作已被用作光学显微镜的固定剂。它需要相对较短的固定时间。它适用于长期储存组织。一旦被正确固定后,组织应该可以承受后续的组织处理或染色阶段。

Packaging

产品包装在一个 10L 的软方桶中,由纸板箱内的塑料气囊和连接的插口组成。

Physical form

中性缓冲的溶液

Biochem/physiol Actions

Formaldehyde is both a non-coagulant and an additive fixative. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins.

Features and Benefits

  • 10% NBF is well-suited for large throughput laboratories.
  • It requires a relatively short period of fixation.
  • It can be used for the long-term storage of tissue.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

wgk

WGK 3

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Histological and Histochemical Methods ? Theory and practice, 5th Edition
J. A. Kiernan
Histological and Histochemical Methods: Theory and Practice (2015)
Ted M Hsu et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(48), 30744-30754 (2020-11-18)
Thirst is a highly potent drive that motivates organisms to seek out and consume balance-restoring stimuli. The detection of dehydration is well understood and involves signals of peripheral origin and the sampling of internal milieu by first order homeostatic neurons
Recapitulating spatiotemporal tumor heterogeneity in vitro through engineered breast cancer microtissues.
Mazio C, et al.
Acta Biomaterialia, 73, 236-249 (2018)
Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.
Hassler M R, et al.
Nucleic Acids Research, 46(5), 2185-2196 (2018)
Quantifying size and number of adipocytes in adipose tissue.
Parlee S D, et al.
Methods in Enzymology, 537, 93-122 (2014)

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