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Merck
CN

HT501320

Sigma-Aldrich

甲醛溶液,中性缓冲,10%

histological tissue fixative

别名:

甲醛

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MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
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生物来源

synthetic

浓度

10% formalin (approx. 4% formaldehyde)

颜色

colorless

pH值(酸碱度)

6.90-7.10

密度

1.080 g/cm3

应用

hematology
histology

储存温度

room temp

SMILES字符串

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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一般描述

10%福尔马林中性缓冲液通常用作已被用作光学显微镜的固定剂。它需要相对较短的固定时间。它适用于长期储存组织。一旦被正确固定后,组织应该可以承受后续的组织处理或染色阶段。

应用

10% 中性缓冲福尔马林溶液已被用作固定组织的常用通用组织学固定剂。
常用的通用组织学固定剂。

生化/生理作用

Formaldehyde is both a non-coagulant and an additive fixative. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins.

特点和优势

  • 10% NBF is well-suited for large throughput laboratories.
  • It requires a relatively short period of fixation.
  • It can be used for the long-term storage of tissue.

包装

产品包装在一个 10L 的软方桶中,由纸板箱内的塑料气囊和连接的插口组成。

外形

中性缓冲的溶液

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

WGK

WGK 3

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Histological and Histochemical Methods ? Theory and practice, 5th Edition
J. A. Kiernan
Histological and Histochemical Methods: Theory and Practice (2015)
Ted M Hsu et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(48), 30744-30754 (2020-11-18)
Thirst is a highly potent drive that motivates organisms to seek out and consume balance-restoring stimuli. The detection of dehydration is well understood and involves signals of peripheral origin and the sampling of internal milieu by first order homeostatic neurons
Recapitulating spatiotemporal tumor heterogeneity in vitro through engineered breast cancer microtissues.
Mazio C, et al.
Acta Biomaterialia, 73, 236-249 (2018)
Quantifying size and number of adipocytes in adipose tissue.
Parlee S D, et al.
Methods in Enzymology, 537, 93-122 (2014)
Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.
Hassler M R, et al.
Nucleic Acids Research, 46(5), 2185-2196 (2018)

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