质量水平
浓度
10% formalin (approx. 4% formaldehyde)
颜色
colorless
pH值(酸碱度)
6.90-7.10
密度
1.080 g/cm3
应用
hematology
histology
储存温度
room temp
SMILES字符串
[O-]#[C+H2]
InChI
1S/CH2O/c1-2/h1H2
InChI key
WSFSSNUMVMOOMR-UHFFFAOYSA-N
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一般描述
10%福尔马林中性缓冲液通常用作已被用作光学显微镜的固定剂。它需要相对较短的固定时间。它适用于长期储存组织。一旦被正确固定后,组织应该可以承受后续的组织处理或染色阶段。10% NBF很适合于高通量的实验室,并只需要一段相对短的固定时间,但也可用于组织的长期储存。福尔马林通过让蛋白质分子交联形成凝胶而固定,使细胞保持生活状态时的形态结构。
应用
10%中性福尔马林溶液是备受欢迎的通用组织学固定剂。通过防止组织腐败、维持其分子结构来保存组织样本。
常用的通用组织学固定剂。
生化/生理作用
Formaldehyde is both a non-coagulant and an additive fixative. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins.
特点和优势
- 10% NBF is well-suited for large throughput laboratories.
- It requires a relatively short period of fixation.
- It can be used for the long-term storage of tissue.
包装
产品包装在一个 20L 的软方桶中,由纸板箱内的塑料气囊和连接的插口组成。
外形
中性缓冲的溶液
警示用语:
Danger
危险分类
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1
WGK
WGK 3
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Because formalin is toxic, carcinogenic, and a poor preserver of nucleic acids, for more than 20 years, there have been numerous attempts to find a substitute, with as many different alternative fixatives, none totally successful. With a fast penetration, formaldehyde
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