I3639
异他林 甲磺酸盐
别名:
4-[1-Hydroxy-2-[(1-methylethyl)amino]butyl]-1,2-benzenediol mesylate salt
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关于此项目
经验公式（希尔记法）:
C13H21NO3 · CH4O3S
化学文摘社编号:
分子量:
335.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
230-695-8
MDL number:
originator
Sanofi Aventis
Quality Segment
storage temp.
2-8°C
SMILES string
CS(O)(=O)=O.CCC(NC(C)C)C(O)c1ccc(O)c(O)c1
InChI
1S/C13H21NO3.CH4O3S/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9;1-5(2,3)4/h5-8,10,13-17H,4H2,1-3H3;1H3,(H,2,3,4)
InChI key
SOYAGMVKMXZVNZ-UHFFFAOYSA-N
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155)
Application
Isoetharine mesylate salt has been used:
- as an adrenergic drug to test its effect on embryo implantation in 4-day pregnant mice
- as a substrate for recombinant human sulfotransferase (SULT) in SULT assay to monitor conjugation reaction
- as a β-2 agonist in collision-induced dissociation (CID) mass spectrometry analysis
Biochem/physiol Actions
Isoetharine is an agonist for β-adrenergic receptors and is a bronchodilator. It is a catecholic drug metabolized by sulfotransferases and is present in human urine and plasma as a sulfated metabolite. Catechol O-methyltransferase (COMT) also mediates the methylation of isoetharine in the metabolic conjugation pathway.
Features and Benefits
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves