I6504
(−)-Isoproterenol hydrochloride
≥98% (TLC), powder, β-adrenoceptor agonist
别名:
(−)-Isoprenaline hydrochloride, (−)-N-Isopropyl-L-noradrenaline hydrochloride, (R)-3,4-Dihydroxy-α-(isopropylaminomethyl)benzyl alcohol hydrochloride
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关于此项目
线性分子式:
3,4-(HO)2C6H3CH(OH)CH2NHCH(CH3)2·HCl
化学文摘社编号:
分子量:
247.72
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
6077193
产品名称
(−)-Isoproterenol hydrochloride,
Quality Segment
mp
175 °C (dec.) (lit.)
solubility
soluble (50 mg/ml: H2O)
storage temp.
−20°C
SMILES string
Cl[H].CC(C)NC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H/t11-;/m0./s1
InChI key
IROWCYIEJAOFOW-MERQFXBCSA-N
Gene Information
human ... ADRB2(154)
Application
(−)-Isoproterenol hydrochloride has been used in in vitro explant culture. It has also been used in transcriptome analysis of heart.
Biochem/physiol Actions
Isoproterenol hydrochloride is useful in post transplantal organ recovery. It exhibits ionotropic and chronotropic effects. With respect to donor heart recovery, isoproterenol hydrochloride decreases peripheral and systemic vascular resistance. Isoproterenol also increases the heart rate.
β-adrenoceptor agonist; increases cytosolic cAMP.
Preparation Note
This material can be dissolved in 50 mg/ml of H2O.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves