(−)-Isoproterenol hydrochloride

Name: (−)-Isoproterenol hydrochloride
Brand: SIGMA

≥98% (TLC), powder, β-adrenoceptor agonist

别名:

(-)-异丙去甲肾上腺素盐酸盐

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About This Item

线性分子式:

3,4-(HO)₂C₆H₃CH(OH)CH₂NHCH(CH₃)₂·HCl

CAS Number:

5984-95-2

分子量:

247.72

Beilstein:

6077193

MDL编号:

MFCD00064548

UNSPSC代码:

12352200

PubChem化学物质编号:

24278495

NACRES:

NA.77

Product Name

(−)-Isoproterenol hydrochloride,

质量水平

200

mp

175 °C (dec.) (lit.)

溶解性

soluble (50 mg/ml: H₂O)

储存温度

−20°C

SMILES字符串

Cl[H].CC(C)NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H/t11-;/m0./s1

InChI key

IROWCYIEJAOFOW-MERQFXBCSA-N

基因信息

human ... ADRB2(154)

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应用

(−)-Isoproterenol hydrochloride has been used in in vitro explant culture. It has also been used in transcriptome analysis of heart.

生化/生理作用

β-adrenoceptor agonist; increases cytosolic cAMP.

Isoproterenol hydrochloride is useful in post transplantal organ recovery. It exhibits ionotropic and chronotropic effects. With respect to donor heart recovery, isoproterenol hydrochloride decreases peripheral and systemic vascular resistance. Isoproterenol also increases the heart rate.