一般描述
分泌成分是单链糖蛋白，可以自由存在或作为分泌免疫球蛋白A（SIgA）的成分存在。IgA调节共生肠道细菌与宿主免疫系统防御之间的生理平衡。它是产生最多的抗体同种型。IgAs主要分泌于肠粘膜，防止共生微生物侵入肠道
单克隆抗分泌成分（IgA）抗体对分泌型人IgA和游离分泌成分具有特异性。该抗体不与人IgG、IgM和IgE结合。
单克隆抗分泌成分（IgA）抗体对分泌型人IgA和游离分泌成分具有特异性。该抗体不与人IgG、IgM和IgE结合。
免疫原
从人初乳中纯化的分泌成分
应用
单克隆抗分泌成分（IgA）抗体已用于免疫组化分析和血清分析。
单克隆抗分泌成分（IgA）抗体适用于EIA和蛋白质印迹。该产品也可用于间接ELISA（1：10,000）。
成功使用该抗体的应用以及相关的同行评审论文如下所示。
染色质免疫沉淀分析（1篇论文）
染色质免疫沉淀分析（1篇论文）
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
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闪点(°C)
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法规信息
常规特殊物品
此项目有
Muna Sapkota et al.
Alcoholism, clinical and experimental research, 41(12), 2093-2099 (2017-09-25)
Malondialdehyde (MDA) and acetaldehyde (AA) exist following ethanol metabolism and tobacco pyrolysis. As such, lungs of individuals with alcohol use disorders (AUDs) are a target for the effects of combined alcohol and cigarette smoke metabolites. MDA and AA form a
Min Zhao et al.
Experimental and therapeutic medicine, 14(5), 4033-4040 (2017-10-28)
Redox imbalance is established in various human diseases. Treatment of intestinal epithelial cells with hyperoxia for a prolonged period of time may cause serious effects on redox balance. Secretory component (SC) protein is secreted by intestinal epithelial cells, and has
Alpha Fardah Athiyyah et al.
Iranian journal of microbiology, 11(4), 300-304 (2019-11-14)
Probiotics and prebiotics are known to regulate immune responses. A synbiotic is a product that combines probiotics and prebiotics in a single dosage form. In this study, we attempt to present the effects of a multispecies synbiotic on intestinal mucosa
C G Engeland et al.
Brain, behavior, and immunity, 52, 11-17 (2015-09-01)
Stress-induced impairments of mucosal immunity may increase susceptibility to infectious diseases. The present study investigated the association of perceived stress, depressive symptoms, and loneliness with salivary levels of secretory immunoglobulin A (S-IgA), the subclasses S-IgA1, S-IgA2, and their transporter molecule
Influence of reactive oxygen species on secretory component in the intestinal epithelium during hyperoxia
Zhao M, et al.
Experimental and Therapeutic Medicine, 14(5), 4033-4040 (2017)
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