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Merck
CN

L4268

脂多糖 来源于肺炎克雷伯氏杆菌

purified by phenol extraction

别名:

LPS

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UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
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biological source

bacterial (Klebsiella pneumoniae)

form

lyophilized powder

purified by

phenol extraction

impurities

<3% Protein (Lowry)

color

white to faint yellow

solubility

water: 4.90-5.10 mg/mL, slightly hazy to turbid, colorless to faintly yellow

shipped in

ambient

storage temp.

2-8°C

Quality Level

General description

该产品是从肺炎克雷伯菌通过苯酚提取而来。源菌株是 ATCC 15380。

Biochem/physiol Actions

脂多糖(LPS)位于膜的外层,并且在非包封菌株中暴露在细胞表面上。它们有助于保持外膜的完整性,并保护细胞免受胆汁盐和亲脂性抗生素的作用。

Preparation Note

本产品可溶于水(5mg/ml)或细胞培养基(1mg/ml),形成浑浊的淡黄色溶液。经过涡旋并升温至 70-80 oC 后,在盐水中可获得浓度更高、但仍然混浊的溶液(20mg/ml)。脂多糖分子在每种溶剂中都会形成胶束。在水和磷酸盐缓冲液中形成浑浊的溶液。在有机溶剂中也不会更清澈。在甲醛中形成具有漂浮物的浑浊悬浮液,而在水中则产生均匀浑浊的溶液。

Other Notes

为了全面了解我们针对客户研究提供的各种脂多糖产品,建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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An increasing body of evidence is indicating that the gut microbiota modulates pulmonary inflammatory responses. This so-called gut-lung axis might be of importance in a whole spectrum of inflammatory pulmonary diseases such as acute respiratory distress syndrome, chronic obstructive pulmonary
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CCAAT/enhancer-binding protein delta (C/EBPδ) is a member of the C/EBP family of transcription factors. According to the current paradigm, C/EBPδ potentiates cytokine production and modulates macrophage function thereby enhancing the inflammatory response. Remarkably, however, C/EBPδ deficiency does not consistently lead
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Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37(3), 927-937 (2016-05-08)
Hepatic encephalopathy has traditionally been considered a reversible disorder. However, recent studies suggested that repeated episodes of hepatic encephalopathy cause persistent impairment leading to neuronal loss. The aims of our study were the development of a new animal model that
Jinling Zhang et al.
Biosensors & bioelectronics, 99, 312-317 (2017-08-09)
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