L5385
α-乳清蛋白 来源于牛奶
Type I, ≥85% (PAGE), lyophilized powder
别名:
Bos d 4, Lactose synthase B protein, alpha-lactalbumin
生物来源
bovine milk
质量水平
类型
Type I
方案
≥85% (PAGE)
表单
lyophilized powder
浓度
≥85 % protein
技术
cell culture | mammalian: suitable
electrophoresis: suitable
杂质
calcium, tested
溶解性
H2O: soluble 10 mg/mL, clear to slightly hazy, colorless to faintly yellow
UniProt登记号
储存温度
−20°C
基因信息
cow ... LALBA(281894)
正在寻找类似产品? 访问 产品对比指南
一般描述
α-乳清蛋白是一种分子量较小的球状乳清蛋白，存在于迄今为止已研究的所有乳汁中。它是在乳腺中产生的约14kDa的金属蛋白。
应用
α-从牛乳中提取的乳清蛋白作为补充剂，用于各种细胞培养的基础培养基。也已作为标记物，用于十二烷基硫酸钠-聚丙烯酰胺凝胶电泳（SDS-PAGE）。
生化/生理作用
α-乳清蛋白是人乳汁中的主要蛋白。它由单个多肽链组成，含有通过二硫键连接的8个半胱氨酸。α-乳清蛋白可结合多种金属离子，包括钙，这一性质被认为在从还原的变性形式再生成天然α-乳清蛋白的过程中发挥重要作用。α-乳清蛋白还具有独特的锌结合位点，其被认为在乳糖合酶复合物的结合中发挥作用。 成熟蛋白质由123个氨基酸残基（14kD）组成，并且具有1.7 Α°分辨率三维结构，含四个α-螺旋和三链反式平行β-折叠。
其可通过改变半乳糖基转移酶的底物特异性以增加乳糖形成的速率；半乳糖基转移酶和 α-乳白蛋白的复合物称为乳糖合酶。
其可通过改变半乳糖基转移酶的底物特异性以增加乳糖形成的速率；半乳糖基转移酶和α-乳白蛋白的复合物称为乳糖合酶。Asp87 或 Asp88 对 Ala 的定点诱变完全消除了强钙结合亲和力，并将乳糖合酶的刺激降低到最大速率的 <3.5%。
分析说明
钙饱和的。可能含有微量的硫酸铵和磷酸钠
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Daniel Rusu et al.
The Journal of nutrition, 140(2), 382-391 (2009-12-25)
Innate immunity depends on the efficiency of neutrophils to be activated rapidly to restore homeostasis. It can benefit from priming agents that enhance neutrophil capacity to respond more efficiently to a subsequent stimulation. Among natural products, a bovine whey protein
XiaoLu Geng et al.
Soft matter, 15(24), 4787-4796 (2019-05-08)
Formation of nanotubes from partially hydrolysed α-lactalbumin (α-La) was investigated at five pH values, two concentrations of α-La and two calcium levels. Nanotubes were formed under almost all combinations of the investigated factors, and for the first time the formation
alpha-Lactalbumin: a calcium metalloprotein.
Y Hiraoka et al.
Biochemical and biophysical research communications, 95(3), 1098-1104 (1980-08-14)
Falk Bernsmann et al.
Journal of colloid and interface science, 344(1), 54-60 (2010-01-23)
We recently showed the possibility to build dopamine-melanin films of controlled thickness by successive immersions of a substrate in alkaline solutions of dopamine [F. Bernsmann, A. Ponche, C. Ringwald, J. Hemmerlé, J. Raya, B. Bechinger, J.-C. Voegel, P. Schaaf, V.
S Goodall et al.
Journal of dairy science, 91(1), 1-10 (2007-12-22)
Synthetic microporous membranes with functional groups covalently attached were used to selectively separate beta-lactoglobulin, BSA, and alpha-lactalbumin from rennet whey. The selectivity and membrane performance of strong (quaternary ammonium) and weak (diethylamine) ion-exchange membranes were studied using breakthrough curves, measurement
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持