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Merck
CN

L6136

Sigma-Aldrich

脂多糖 来源于粘质沙雷氏菌

purified by phenol extraction

别名:

LPS

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关于此项目

MDL编号:
UNSPSC代码:
12352201
NACRES:
NA.25
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生物来源

Serratia marcescens

质量水平

表单

lyophilized powder

纯化方式

phenol extraction

杂质

<3% Protein (Lowry)

颜色

white to yellow cast

溶解性

water: 4.90-5.10, faintly hazy to hazy, colorless to faint yellow or tan

运输

ambient

储存温度

2-8°C

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一般描述

本品为从粘质沙雷氏菌中提取的苯酚。源菌株是ATCC 21639。

生化/生理作用

脂多糖(LPS)位于膜的外层,并且暴露在无包膜菌株的细胞表面。它们有助于维持外层膜的完整性,并保护细胞免受胆汁盐和亲脂性抗生素的破坏。

制备说明

本品溶于水(5 mg/ml)或细胞培养基(1 mg/ml),得到浑浊的淡黄色溶液。以盐水为溶剂时,经过涡旋并加热至70-80 oC后,得到浓度更高但仍然浑浊的溶液(20 mg/ml)。脂多糖分子可在各种溶剂中形成胶束。在水和磷酸盐缓冲盐水中,可观察到混浊的溶液。使用有机溶剂不会得到更澄清的溶液。以甲醇为溶剂将得到含漂浮物的混浊悬浮液,而以水为溶剂将得到均匀的混浊溶液。

其他说明

为了全面了解我们针对客户研究提供的各种脂多糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mollie R Sorrell et al.
Journal of insect physiology, 126, 104097-104097 (2020-08-14)
Fragile X syndrome (FXS), caused by a mutation in the Fragile X Mental Retardation 1 (FMR1) gene, is a common form of inherited mental retardation. Mutation of the gene leads to a loss of the gene product Fragile X Mental Retardation Protein (FMRP). While a loss
H Heremans et al.
American journal of respiratory and critical care medicine, 161(1), 110-117 (2000-01-05)
Mice given lipopolysaccharide (LPS) intravenously developed lung edema, which was maximum after 6 h. Tumor necrosis factor, interleukin 12 (IL-12), IL-6, and interferon-gamma (IFN-gamma) appeared in the serum, and levels of nitrogen oxide (NO) derivatives were increased in serum and
M G Zenobi et al.
Journal of dairy science, 103(3), 2200-2216 (2020-01-20)
Objectives were to evaluate the effect of prepartum energy intake and peripartal supplementation of ruminally protected choline (RPC) on select indicators of immune status in blood plasma and on lipopolysaccharide-stimulated blood cells ex vivo. At 47 ± 6 d before
Ching-Hua Hsieh et al.
Journal of biomedical science, 19, 69-69 (2012-08-02)
Lipopolysaccharide (LPS) is recognized as the most potent microbial mediator presaging the threat of invasion of Gram-negative bacteria that implicated in the pathogenesis of sepsis and septic shock. This study was designed to examine the microRNA (miRNA) expression in whole
Matthew Stephens et al.
Gut microbes, 11(3), 421-432 (2019-06-18)
Patients presenting with Inflammatory bowel disease have been shown to exhibit an altered microbiome in both Crohn's disease and Ulcerative colitis. This shift in the microbial content led us to question whether several of these microbes are important in inflammatory

商品

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

相关内容

Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.

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