产品名称
脂多糖 来源于伤寒沙门氏菌, purified by phenol extraction
biological source
bacterial (Salmonella typhosa)
form
lyophilized powder
purified by
phenol extraction
impurities
<3% Protein (Lowry)
color
white to yellow cast
solubility
water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
shipped in
ambient
storage temp.
2-8°C
Quality Level
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Application
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征成分。LPS 及其脂质 A 部分通过 Toll 样受体 4（TLR4）刺激先天免疫系统的细胞，TLR4 是 Toll 样受体蛋白家族的成员，它能识别常见的病原体相关分子模式（PAMP）。
Biochem/physiol Actions
脂多糖（LPS）位于膜的外层，并且在非包封的菌株中暴露在细胞表面上。它们有助于外膜的完整性，并保护细胞免受胆汁盐和亲脂性抗生素的作用。
General description
本产品是从伤寒沙门氏菌中提取的苯酚。来源菌株为 ATCC 10749。
Preparation Note
产物可溶于水（5mg/ml）或细胞培养基（1mg/ml），产生浑浊的淡黄色溶液。在经过涡旋，并升温至 70-80oC 后，含水盐水变得更浓缩，但仍然浑浊（20mg/ml）。脂多糖分子在每种溶剂中均形成胶束。在水和磷酸盐缓冲盐水中观察到浑浊的溶液。使用有机溶剂，溶液也是浑浊的。甲醇产生具有漂浮物的浑浊悬浮液，而水则产生均匀浑浊的溶液。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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