产品名称
脂多糖 来源于肠沙门氏菌 肠炎血清型, γ-irradiated, BioXtra, suitable for cell culture
purified by
gel-filtration chromatography
technique(s)
cell culture | mammalian: suitable
biological source
Salmonella enterica (Serotype enteritidis)
sterility
γ-irradiated
product line
BioXtra
form
lyophilized powder
impurities
<1% Protein (Lowry)
color
white to yellow cast
solubility
water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless
storage temp.
2-8°C
Quality Level
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Application
来自血清型肠炎沙门氏菌的脂多糖可用于细胞培养和细胞结合应用。它被用于研究炎症在神经病理性疼痛和动脉瘤进展中的作用。
脂多糖 (LPS) 是革兰氏阴性菌细胞壁的特征性成分。LPS 及其脂质 A 部分通过 Toll 样受体 4 (TLR4) 刺激天然免疫系统的细胞。
Biochem/physiol Actions
脂多糖(LPS)是革兰氏阴性细菌细胞壁的特征组分。LPS及其脂质A部分可通过Toll样受体4(TLR4)刺激细胞的先天免疫系统,Toll样受体4是Toll样受体蛋白家族的成员,其可识别常见的病原体相关分子模式(PAMP)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Rosemary Fernandez et al.
Bio-protocol, 5(11) (2016-05-03)
The ability to assess the function of a range of cytokine, antigen receptor, and Toll-like receptor (TLR) signaling pathways in a range of immune cells could provide a kind of fingerprint of the state of the human immune system. The
Elisabetta Liverani et al.
Journal of leukocyte biology, 95(2), 313-323 (2013-10-22)
Thienopyridines are a class of antiplatelet drugs that are metabolized in the liver to several metabolites, of which only one active metabolite can irreversibly antagonize the platelet P2Y12 receptor. Possible effects of these drugs and the role of activated platelets
Anita Mikołajczyk et al.
Toxins, 11(2) (2019-02-06)
Bacterial lipopolysaccharide (LPS) can contribute to the pathogenesis and the clinical symptoms of many diseases such as cancer, mental disorders, neurodegenerative as well as metabolic diseases. The asymptomatic carrier state of Salmonella spp. is a very important public health problem.
Christopher J Neufeldt et al.
PLoS pathogens, 9(10), e1003744-e1003744 (2013-11-10)
Hepatitis C virus (HCV) infection induces formation of a membranous web structure in the host cell cytoplasm where the viral genome replicates and virions assemble. The membranous web is thought to concentrate viral components and hide viral RNA from pattern
Anita Mikołajczyk et al.
Gut pathogens, 9, 73-73 (2017-12-20)
The present research was conducted to investigate the influence of a low, single dose of LPS, which does not result in any clinical symptoms of intoxication on the expression of selected neuropeptides within the intestines of the domestic pig. This
商品
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
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