SMILES string
O1[C@]([C@H]([C@@H]([C@H]1CO[C@@]3(O[C@@H]([C@H]([C@@H]3O)O)CO)CO)O)O)(OC[C@H]2O[C@]([C@H]([C@@H]2O)O)(O)CO)CO
InChI
1S/C18H32O16/c19-1-7-10(23)14(27)17(5-21,33-7)31-3-9-12(25)15(28)18(6-22,34-9)30-2-8-11(24)13(26)16(29,4-20)32-8/h7-15,19-29H,1-6H2/t7-,8-,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-/m1/s1
InChI key
ZFTFOHBYVDOAMH-XNOIKFDKSA-N
biological source
bacterial (Erwinia herbicola)
assay
≥98% (TLC)
form
powder
technique(s)
thin layer chromatography (TLC): suitable
color
white
solubility
water: 9.80-10.20 mg/mL, cloudy to hazy, colorless to faintly yellow
storage temp.
2-8°C
Quality Level
General description
Levan果聚糖是产自某些微生物和植物的多糖。它是果糖分子以β-(2→6)形式连接而成的非典型生物聚合物。Levan果聚糖是一种胞外多糖（细胞外合成）。
Application
Levan果聚糖（来源于草生欧文氏菌Erwinia herbicola）已用于：
- 作为核磁共振波谱法(NMR)的标准品，分析甜菜糖蜜培养基中地衣芽孢杆菌Bacillus licheniformis NS032生产的levan果聚糖
- 作为多糖底物，检测科普里普氏菌Prevotella copri菌株以多糖为唯一碳源的体外生长能力
- 作为果聚糖酶活性检测底物
Biochem/physiol Actions
Levan果聚糖可用于化妆品、药品或纳米技术等多种工业应用。具有抗高血糖和抗肿瘤作用，可防止糖尿病诱导的氧化应激，可提高心脏中的过氧化氢酶(CAT)和超氧化物歧化酶(SOD)水平。Levan果聚糖还具有免疫调节和益生作用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Susanne L Jensen et al.
International journal of biological macromolecules, 85, 514-521 (2016-01-17)
A Levanase, LevB, from Bacillus subtilis 168, was expressed as a His6-tagged protein in Escherichia coli. The enzyme was purified and characterised for its activity and substrate specificity. LevB has a pH optimum of 6.0-6.5 and a maximum observed specific
An evaluation of the prebiotic potential of microbial levans from Erwinia sp. 10119
Liu C, et al.
Journal of functional foods, 64, 103668-103668 (2020)
Hannah Fehlner-Peach et al.
Cell host & microbe, 26(5), 680-690 (2019-11-15)
Gut-dwelling Prevotella copri (P. copri), the most prevalent Prevotella species in the human gut, have been associated with diet and disease. However, our understanding of their diversity and function remains rudimentary because studies have been limited to 16S and metagenomic surveys
Álvaro González-Garcinuño et al.
Microbial cell factories, 16(1), 91-91 (2017-05-26)
Levan has been traditionally produced from microorganism. However, there is a continuous effort in looking for new strains that improve levan production yield and uses alternative sugar sources for growth. Despite having a wide range of data about levan yield
Faruk Küçükaşik et al.
Applied microbiology and biotechnology, 89(6), 1729-1740 (2010-12-17)
Levan is a homopolymer of fructose with many outstanding properties like high solubility in oil and water, strong adhesiveness, good biocompatibility, and film-forming ability. However, its industrial use has long been hampered by costly production processes which rely on mesophilic
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