Name: (±)-Muscarine chloride hydrate
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₉H₂₀ClNO₂ · xH₂O

CAS Number:

2936-25-6

分子量:

209.71 (anhydrous basis)

MDL编号:

MFCD00055067

UNSPSC代码:

12352200

PubChem化学物质编号:

24278578

NACRES:

NA.77

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质量水平

100

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white

溶解性

deionized water: ≥20 mg/mL

储存温度

room temp

SMILES字符串

[Cl-].CC1OC(CC1O)C[N+](C)(C)C

InChI

1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1

InChI key

WUFRNEJYZWHXLC-UHFFFAOYSA-M

基因信息

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

应用

(±)-Muscarine chloride hydrate may be used:

as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments
as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples

生化/生理作用

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.

Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.

特点和优势

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.