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Merck
CN

M1272

Sigma-Aldrich

Anti-Mouse IgA (α-chain specific) antibody produced in sheep

affinity isolated antibody, lyophilized powder

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MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46
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生物来源

sheep

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

secondary antibodies

克隆

polyclonal

表单

lyophilized powder

技术

Ouchterlony double diffusion: suitable

储存温度

2-8°C

靶向翻译后修饰

unmodified

一般描述

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Anti-Mouse IgA (α-chain specific) is specific for α chain of mouse IgA.

免疫原

Purified mouse IgA (myeloma protein)

应用

Anti-Mouse IgA (α-chain specific) is suitable for Ouchterlony Double Diffusion. The antibody was used to detect antigens to Helicobacter hepaticus in mice serum using a concentration of 5 μg/ml.

外形

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2

制备说明

Reconstitute with 0.135 M sodium chloride.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Mark T Whary et al.
Immunology, 133(2), 165-178 (2011-03-24)
To model inflammatory bowel disease, we assessed infection with Helicobacter hepaticus 3B1 (ATCC 51449) and a potential probiotic Lactobacillus reuteri (ATCC PTA-6475) in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(-/-) ) mice. No typhlocolitis developed in germ-free controls (n=21) or in L. reuteri (n=8)
Jan Holmgren et al.
Nature medicine, 11(4 Suppl), S45-S53 (2005-04-07)
There is currently great interest in developing mucosal vaccines against a variety of microbial pathogens. Mucosally induced tolerance also seems to be a promising form of immunomodulation for treating certain autoimmune diseases and allergies. Here we review the properties of

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