产品名称
抗 小鼠 IgG（Fc 特异性） 山羊抗, 2.0 mg/mL, affinity isolated antibody
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
concentration
2.0 mg/mL
technique(s)
indirect ELISA: 1:15,000
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
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Application
小鼠抗IgG（Fc特异性）抗体可用于：
- 酶联免疫吸附测定 (ELISA)
- Ouchterlony双向扩散试验
- 抗药抗体免疫分析
- 免疫电泳
Biochem/physiol Actions
免疫球蛋白G（IgG）是一种糖蛋白抗体，可调节免疫反应（如吞噬作用），也可影响自身免疫疾病的进程。小鼠IgG具有四种不同的亚型，即IgG1、IgG2a、IgG2b和IgG3。IgG1可调节小鼠的补体结合
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
IgG亚型是免疫系统中最丰富的血清免疫球蛋白。它由B细胞分泌，存在于血液和细胞外液中。
Immunogen
小鼠IgG，Fc片段
Other Notes
经过人IgG和大鼠血清蛋白吸附的抗体
Physical form
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
Preparation Note
经过吸附以减少人或大鼠样本的背景染色。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Development and validation of a standardized ELISA for the detection of soluble Fc-epsilon-RI in human serum
Lexmond W, et al.
Journal of Immunological Methods, 373(1-2), 192-199 (2011)
Integrating molecular detection and response to create self-signalling antibodies
Randle B, et al.
Biochemical and Biophysical Research Communications, 324(2), 504-510 (2004)
Nathan H Joh et al.
Journal of pharmaceutical sciences, 109(1), 845-853 (2019-10-20)
Silicone oil is a lubricant for prefilled syringes (PFS), a common primary container for biotherapeutics. Silicone oil particles (SiOP) shed from PFS are a concern for patients due to their potential for increased immunogenicity and therefore also of regulatory concern.
Universal immunoassay applied during early development of large molecules to understand impact of immunogenicity on biotherapeutic exposure
Bautista AC, et al.
The APPS Journal, 14(4), 843-849 (2012)
Christiano M V Barbosa et al.
Cell death discovery, 5, 135-135 (2019-09-26)
Annexin A1 (AnxA1) modulates neutrophil life span and bone marrow/blood cell trafficking thorough activation of formyl-peptide receptors (FPRs). Here, we investigated the effect of exogenous AnxA1 on haematopoiesis in the mouse. Treatment of C57BL/6 mice with recombinant AnxA1 (rAnxA1) reduced
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