M3696
Anti-MAP2 Antibody
rabbit polyclonal
别名:
抗 微管相关蛋白 2
登录 查看组织和合同定价。
选择尺寸
关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
FACS, IHC, WB
Citations:
64
产品名称
抗 MAP2 兔抗, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~280 kDa, antigen ~72 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
flow cytometry: 1:200-1:500, immunohistochemistry: 1:100-1:200, western blot: 1:500-1:1,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MAP2(4133)
mouse ... Mtap2(17756)
rat ... Map2(25595)
General description
MAP2 是一种与微管相关的蛋白，调节细胞骨架的结构和功能。该蛋白也调节神经元的形态发生和细胞增殖。MAP2和F-actin的相互作用与神经突初生（neurite initiation）和微管再组装有关。MAP2 的水平下降与传染性海绵状脑病相关。抗MAP2抗体对于人、小鼠和大鼠MAP2有特异性。
微管相关蛋白 2 (Microtubule associated protein 2，MAP2) 是一种神经元特异性蛋白，在中枢神经系统中广泛表达。它是细胞骨架蛋白中的一员。 该基因位于人类染色体 2q34 上。
Immunogen
相应的人 MAP2 残基 2-15 的合成肽。
Application
兔抗 MAP2 抗体可用于免疫细胞化学。
抗 MAP2 抗体适用于免疫组织化学（1:500，使用 Zamboni 固定剂固定、冷冻的小鼠脊髓和丘脑切片）、流式细胞术 (1:200-1:500)、免疫印迹（约 72 kDa 和 280 kDa）和蛋白质印迹 (1:500-1:1,000)。
Biochem/physiol Actions
微管相关蛋白2（MAP2）在星形胶质细胞和少突胶质细胞中树突状突起的形成过程中起关键作用。它可以维持微管的稳态。该蛋白在神经可塑性中起重要作用。
Physical form
溶剂为含有0.02％叠氮化钠的磷酸盐缓冲盐水。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
低风险生物材料
常规特殊物品
此项目有
Qinghai Liu et al.
PloS one, 11(4), e0153376-e0153376 (2016-04-14)
This study examines the effects of nano-size particulate matter (nPM) exposure in the setting of murine reperfused stroke. Particulate matter is a potent source of inflammation and oxidative stress. These processes are known to influence stroke progression through recruitment of
Leif Dehmelt et al.
Genome biology, 6(1), 204-204 (2005-01-12)
Microtubule-associated proteins (MAPs) of the MAP2/Tau family include the vertebrate proteins MAP2, MAP4, and Tau and homologs in other animals. All three vertebrate members of the family have alternative splice forms; all isoforms share a conserved carboxy-terminal domain containing microtubule-binding
Rouhollah Habibey et al.
Scientific reports, 7(1), 8558-8558 (2017-08-19)
Due to their small dimensions, electrophysiology on thin and intricate axonal branches in support of understanding their role in normal and diseased brain function poses experimental challenges. To reduce experimental complexity, we coupled microelectrode arrays (MEAs) to bi-level microchannel devices
Molecular analysis of cellular loci disrupted by papillomavirus 16 integration in cervical cancer: frequent viral integration in topologically destabilized and transcriptionally active chromosomal regions
Choo KB, et al.
Journal of Medical Virology, 49(1), 15-22 (1996)
Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells
Zhou Y, et al.
Neuro-Oncology, 17(12), 1578-1588 (2015)
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持