M4773
间羟胺 (+)-酒石酸氢盐
α-adrenoceptor agonist
别名:
阿拉明 酒石酸氢盐
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关于此项目
经验公式（希尔记法）:
C9H13NO2 · C4H6O6
化学文摘社编号:
分子量:
317.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
251-502-3
MDL number:
Quality level:
产品名称
间羟胺 (+)-酒石酸氢盐,
Quality Level
originator
Merck & Co., Inc., Kenilworth, NJ, U.S.
SMILES string
O[C@H]([C@@H](O)C(O)=O)C(O)=O.C[C@H](N)[C@H](O)c1cccc(O)c1
InChI
1S/C9H13NO2.C4H6O6/c1-6(10)9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-6,9,11-12H,10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t6-,9-;1-,2-/m01/s1
InChI key
VENXSELNXQXCNT-IJYXXVHRSA-N
Application
Metaraminol (+)-bitartrate salt has been used to study the effects of adrenergic agonists in the mouse model of endometriosis.
Biochem/physiol Actions
α-adrenoceptor agonist.
Metaraminol may serve as a false sympathetic transmitter. It is a mixed α - and β-adrenergic agonist.
Metaraminol may serve as a false sympathetic transmitter. It is a mixed α - and β-adrenergic agonist.
Features and Benefits
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
T P Haydon et al.
Anaesthesia and intensive care, 36(5), 736-738 (2008-10-16)
We report the case of a 51-year-old woman receiving endobronchial treatment with neodymium:yttrium garnet laser After 30 minutes of stable anaesthesia and laser treatment, sudden inferior myocardial ischaemia developed followed by haemodynamic collapse. Resuscitation with fluids, pressors, atropine and esmolol
S Y Yeh
Physiology & behavior, 68(1-2), 227-234 (2000-01-08)
Structure-anorectic activity relationship of two substituted amphetamines has been investigated in this study. Literature reports showed conflicting results in their anorectic activities in spite of the similarity in chemical structures of metaraminol and phenylephrine. Hence, the effects of alpha-carbon atom
Ying Huang et al.
Se pu = Chinese journal of chromatography, 28(11), 1084-1088 (2011-03-09)
A method for the determination of three adrenergic drugs, including phenylephrine hydrochloride (PHE), metaraminol bitartrate (MR) and isoprenaline hydrochloride (IP), was developed using capillary electrophoresis with amperometric detection. The detection potential of working electrode was 0.950 V versus the reference
Chronic stress accelerates the development of endometriosis in mouse through adrenergic receptor beta2
Long Q, et al.
Human Reproduction, 31(11), 2506-2519 (2016)
E T Yamaguchi et al.
International journal of obstetric anesthesia, 20(3), 224-228 (2011-06-07)
The aim of this study was to determine serum oxytocin concentrations following different regimens of prophylactic oxytocin administration in women undergoing elective caesarean delivery. Thirty healthy pregnant patients were randomized, after clamping of the umbilical cord, to receive intravenous oxytocin
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M4773-1G | 04061825982496 |
| M4773-5G | 04061832091976 |
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