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Merck
CN

M4773

Sigma-Aldrich

间羟胺 (+)-酒石酸氢盐

α-adrenoceptor agonist

别名:

阿拉明 酒石酸氢盐

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关于此项目

经验公式(希尔记法):
C9H13NO2 · C4H6O6
化学文摘社编号:
分子量:
317.29
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

间羟胺 (+)-酒石酸氢盐,

创始人

Merck & Co., Inc., Kenilworth, NJ, U.S.

SMILES字符串

O[C@H]([C@@H](O)C(O)=O)C(O)=O.C[C@H](N)[C@H](O)c1cccc(O)c1

InChI

1S/C9H13NO2.C4H6O6/c1-6(10)9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-6,9,11-12H,10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t6-,9-;1-,2-/m01/s1

InChI key

VENXSELNXQXCNT-IJYXXVHRSA-N

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应用

Metaraminol (+)-bitartrate salt has been used to study the effects of adrenergic agonists in the mouse model of endometriosis.

生化/生理作用

α-adrenoceptor agonist.
Metaraminol may serve as a false sympathetic transmitter. It is a mixed α - and β-adrenergic agonist.

特点和优势

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

α-Adrenergic effects on Na+-K+ pump current in guinea-pig ventricular myocytes.
Wang, Y., et al.
The Journal of Physiology, 509, 509-509 (1998)
Steven M Bishop et al.
Anesthesiology, 117(4), 810-821 (2012-08-24)
Physiologic instability is a common clinical problem in the critically ill. Many natural feedback systems are nonlinear, and seemingly random fluctuations may result from the amplification of external perturbations or even arise de novo as a consequence of their underlying
A Khavandi et al.
Anaesthesia, 64(5), 563-566 (2009-05-06)
A 31-year-old female with no risk factors for cardiac disease suffered a peri-operative myocardial infarction during an elective gynaecological procedure under spinal anaesthesia. The timing and nature of cardiac symptoms suggest that the myocardial infarction was caused by coronary artery
Comparison of metaraminol and ephedrine infusions for maintaining arterial pressure during spinal anesthesia for elective cesarean section
Kee W D N, et al.
Anesthesiology, 95(2), 307-313 (2001)
Chronic stress accelerates the development of endometriosis in mouse through adrenergic receptor beta2
Long Q, et al.
Human Reproduction, 31(11), 2506-2519 (2016)

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