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经验公式(希尔记法):
C6H12O6
化学文摘社编号:
分子量:
180.16
UNSPSC Code:
12352201
NACRES:
NA.75
PubChem Substance ID:
EC Number:
222-392-4
Beilstein/REAXYS Number:
1564373
MDL number:
biological source
plant (Spruce, Birch or Beech Wood, Glucose)
product line
BioReagent
assay
≥99%
form
powder
technique(s)
cell culture | mammalian: suitable
Quality Level
solubility
H2O: 50 mg/mL
application(s)
agriculture
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General description
Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.
Application
Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.
D-(+)-Mannose has been used:
- as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
- as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
- in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines
Biochem/physiol Actions
Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Metabolic manipulation of glycosylation disorders in humans and animal models
Freeze HH and Sharma V
Seminars in Cell & Developmental Biology, 21(6), 655-662 (2010)
Agrobacterium-mediated transformation of Sorghum bicolor using immature embryos
Transgenic Plants, 109-122 (2012)
M J Carlino et al.
Gut microbes, 12(1), 1-21 (2020-11-03)
Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic Escherichia coli (EPEC) in 12-29% of diarrheal stool samples from all age groups in developed nations. The aim of this study
Essentials of Carbohydrate Chemistry by John F. Robyt
Pendarvis R
The Chemical Educator, 3(5), 1-2 (1998)
Golgi glycosylation
Stanley P
Cold Spring Harbor Perspectives in Biology, 3(4), a005199-a005199 (2011)
商品
Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.
Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.
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