M6876
D-甘露糖 6-磷酸 二钠盐 水合物
≥97.0% dry basis (enzymatic)
别名:
Sodium (2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate
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关于此项目
经验公式（希尔记法）:
C6H11Na2O9P · xH2O
化学文摘社编号:
分子量:
304.10 (anhydrous basis)
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25
产品名称
D-甘露糖 6-磷酸 二钠盐 水合物, ≥97.0% dry basis (enzymatic)
Quality Level
SMILES string
[Na+].[Na+].[H]O[H].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O
InChI
1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5+,6?;;;/m1.../s1
InChI key
UUWJZXLTPORJKW-XTAHGNKUSA-L
biological source
wood (birch wood)
assay
≥97.0% dry basis (enzymatic)
form
powder
impurities
≤1.0% total fructose 6-phosphate and glucose 6-phosphate
color
white to off-white
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
cation traces
Na: 13.2-17.0% (dry basis)
storage temp.
−20°C
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Application
Mannose has been used in a study to assess the phenotyping of primary human microglia. It has also been used in a study to investigate the identification of Anogeissus latifolia Wallich and analyze refined gum ghatti.
General description
Mannose is a monosaccharide.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Jeroen Melief et al.
Glia, 60(10), 1506-1517 (2012-06-29)
Much is still unknown about mechanisms underlying the phenotypical and functional versatility of human microglia. Therefore, we developed a rapid procedure to isolate pure microglia from postmortem human brain tissue and studied their immediate ex vivo phenotype and responses to
Yunpeng Liu et al.
The Journal of organic chemistry, 76(21), 8682-8689 (2011-10-01)
Mannose-6-phosphate (M6P) containing N-linked glycans are the essential targeting signals for hydrolases sorting in eukaryotic cells. To facilitate their structural and binding analyses, a highly efficient and convergent method has been developed to prepare complex N-linked glycans with well-defined M6P
Wei Cheong Ngeow et al.
Journal of anatomy, 219(5), 638-645 (2011-08-05)
Microsurgical repair of transected peripheral nerves is compromised by the formation of scar tissue and the development of a neuroma, thereby limiting the success of regeneration. The aim of this study was to quantify histomorphometrically the structural changes in neural
Synthesis of mannose-6-phosphate analogues and their utility as angiogenesis regulators.
Véronique Barragan-Montero et al.
ChemMedChem, 6(10), 1771-1774 (2011-07-28)
Petra Tiels et al.
Nature biotechnology, 30(12), 1225-1231 (2012-11-20)
Lysosomal storage diseases are treated with human lysosomal enzymes produced in mammalian cells. Such enzyme therapeutics contain relatively low levels of mannose-6-phosphate, which is required to target them to the lysosomes of patient cells. Here we describe a method for
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