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Merck
CN

M6882

甲基α-D-吡喃甘露糖苷

≥99.0% (HPLC)

别名:

α-甲基D-甘露糖苷

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关于此项目

经验公式(希尔记法):
C7H14O6
化学文摘社编号:
分子量:
194.18
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
210-502-3
Beilstein/REAXYS Number:
81566
MDL number:
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产品名称

甲基α-D-吡喃甘露糖苷, ≥99.0% (HPLC)

InChI key

HOVAGTYPODGVJG-VEIUFWFVSA-N

InChI

1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1

SMILES string

CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

assay

≥99.0% (HPLC)

form

powder

optical activity

[α]20/D 77.0 to 82.0°, c = 1-10% (w/v) in water

technique(s)

HPLC: suitable

color

white to off-white

mp

193-196 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

storage temp.

15-25°C

Quality Level

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Application

已经使用甲基 α-D-吡喃甘露糖苷合成一系列三- 和四羟基化的七元亚氨基糖,该研究致力于具有 D-甘露糖构型的稳定的诺罗霉素类似物。 它也被用于研究普拉定霉素 A 的主要甘露糖结合位点。

General description

甲基 α-D-吡喃甘露糖苷是大肠杆菌结合甘露糖的竞争抑制剂。

Other Notes

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

404.1 °F

flash_point_c

206.74 °C

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Julia Deschamp et al.
Bioorganic & medicinal chemistry, 20(2), 641-649 (2010-10-26)
Noeuromycin is a highly potent albeit unstable glycosidase inhibitor due to its hemiaminal function. While stable D-gluco-like analogs have been reported, no data are available for D-manno-like structures. A series of tri- and tetrahydroxylated seven-membered iminosugars displaying either a D-manno-or
Yu Nakagawa et al.
Journal of the American Chemical Society, 133(43), 17485-17493 (2011-09-29)
Pradimicin A (PRM-A) is an actinomycete-derived antibiotic with the lectin-like property of being able to recognize D-mannopyranoside (Man) in the presence of Ca(2+) ion. PRM-A and its derivatives have been attracting a great deal of attention as the only family
M Aronson et al.
The Journal of infectious diseases, 139(3), 329-332 (1979-03-01)
Methyl alpha-D-mannopyranoside (alpha MM), a competitor inhibitor of the binding of mannose by Escherichia coli, was tested for its ability to prevent infection of the urinary tract of mice with infective strains of the organisms. Injection of the bacteria in
Karen T Welch et al.
Bioorganic & medicinal chemistry letters, 18(24), 6573-6575 (2008-11-08)
A virtual screening approach was used to identify new glycomimetics. The National Cancer Institute Diversity Set was docked into the carbohydrate binding site of the lectin concanavalin A (ConA). The resulting poses were analyzed and 19 molecules were tested for
Oliver Schwardt et al.
Bioorganic & medicinal chemistry, 19(21), 6454-6473 (2011-10-04)
Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is one of the most prevalent infectious diseases. Particularly affected are women, who have a 40-50% risk to experience at least one symptomatic UTI episode at some time during their

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