biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
form
buffered aqueous solution
technique(s)
indirect ELISA: 1:20,000
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
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General description
免疫球蛋白G(IgG)属于免疫球蛋白家族,是一种广泛表达的血清抗体。免疫球蛋白是由两条重链和两条轻链通过二硫键连接而成的。它主要用于帮助免疫防御。它是一种糖蛋白。IgG是一种主要的免疫球蛋白。小鼠具有五种类型的免疫球蛋白:IgM,IgG,IgA,IgD和IgE。小鼠IgG进一步分为五类:IgG1、IgG2a、IgG2b、IgG2c和IgG3。
小鼠 IgG 是由其重链定义的血浆 B 细胞来源抗体同种型。IgG 是在小鼠血清中发现的含量最高的抗体同种型。IgG 穿过胎盘屏障,是一种补体激活剂,与吞噬细胞上的 Fc 受体结合。IgG 级别可随疾病状态感染状态而变化。
山羊多克隆抗小鼠 IgG(Fab 特异性)与正常小鼠血清、小鼠 IgG 和小鼠 IgG 的 Fab 断片反应,但并未观察到与小鼠 IgG 的 Fc 断片的反应。未观察到与人IgG的反应。
Application
山羊多克隆抗小鼠 IgG(Fab 特异性)可用于检测和定量血清和生物体液中的小鼠 IgG。可用于监测感染等多种条件下 IgG 水平的变化。当与检测器分子偶联时,也可作为二抗使用。
山羊抗小鼠IgG(Fab特异性)抗体可用于蛋白印迹。
Biochem/physiol Actions
免疫球蛋白G(IgG)参与II型和III型超敏反应。IgG2a 具有亲细胞特性,IgG2a分子能够激活补体系统。IgG有助于调理素作用、补体结合和抗体依赖型细胞介导的细胞毒性作用。
Physical form
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
Preparation Note
经过吸附以减少人体样本的背景染色。
Other Notes
人IgG吸附抗体。
Disclaimer
除非我们的目录或随附于产品的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
低风险生物材料
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