M7802
单克隆抗MAP激酶，活化/单磷酸化（磷酸苏氨酸ERK-1&2） 小鼠抗
~2 mg/mL, clone ERK-PT115, purified immunoglobulin, buffered aqueous solution
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关于此项目
Conjugate:
unconjugated
Clone:
ERK-PT115, monoclonal
Application:
capture ELISA
immunocytochemistry
microarray
western blot
immunocytochemistry
microarray
western blot
Species reactivity:
rat, human
Citations:
16
Technique(s):
capture ELISA: suitable
immunocytochemistry: suitable
microarray: suitable
western blot: 0.5 μg/mL using extract of a rat fibroblast cell line, Rat1, activated with sorbitol
immunocytochemistry: suitable
microarray: suitable
western blot: 0.5 μg/mL using extract of a rat fibroblast cell line, Rat1, activated with sorbitol
Uniprot accession no.:
产品名称
单克隆抗MAP激酶，活化/单磷酸化（磷酸苏氨酸ERK-1&2） 小鼠抗, ~2 mg/mL, clone ERK-PT115, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
ERK-PT115, monoclonal
form
buffered aqueous solution
mol wt
antigen, ERK-1 44 kDa
antigen, ERK-2 42 kDa
species reactivity
rat, human
concentration
~2 mg/mL
technique(s)
capture ELISA: suitable
immunocytochemistry: suitable
microarray: suitable
western blot: 0.5 μg/mL using extract of a rat fibroblast cell line, Rat1, activated with sorbitol
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MAPK1(5594), MAPK3(5595)
rat ... Mapk1(116590), Mapk3(50689)
Application
小鼠源单克隆抗MAP激酶，活化/单磷酸化（磷酸苏氨酸ERK-1&2）抗体可用于：
- 免疫印迹
- 蛋白质印迹
- 免疫荧光
- 酶联免疫吸附试验（ELISA）
- 免疫化学
Biochem/physiol Actions
该抗体可与单磷酸化苏氨酸和活性二磷酸化形式的MAP激酶（ERK-1和ERK-2）发生特异性反应。它不识别MAP激酶分子的非磷酸化形式或JNK和p38 MAPK的二磷酸化形式。该抗体识别的表位包含活性MAP激酶（例如ERK-2中的Thr183）调节位点内的磷酸化苏氨酸残基。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
活化/单磷酸化（磷酸苏氨酸 ERK-1&2）（小鼠 IgG1亚型）来源于ERK-PT115杂交瘤，该杂交瘤是由小鼠骨髓瘤细胞和来自用合成肽免疫的 BALB/c 小鼠的脾细胞融合产生的。丝裂原活化的蛋白激酶1（MAPK1）定位于人染色体22q11.22，而MAPK3存在于人染色体16p11.2上。
Immunogen
对应于 ERK 活化环磷酸化形式的合成肽HTGFLpTEYVAT。
Physical form
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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