产品名称
抗-肌球蛋白IIA,非肌肉 兔抗, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~200 kDa
species reactivity
rat, human, canine
packaging
antibody small pack of 25 μL
technique(s)
indirect immunofluorescence: 1:100 using cultured rat NRK cells
microarray: suitable
western blot: 1:1,000 using whole cell extracts of cultured dog MDCK kidney cells and cultured human Jurkat cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MYH9(4627)
rat ... Myh9(25745)
Application
兔产生的抗肌球蛋白IIA抗体已用于:
- 免疫荧光
- 免疫组化
- 固定细胞染色/免疫荧光染色
- 免疫印迹
- 免疫沉淀
Biochem/physiol Actions
非肌肉肌球蛋白II参与细胞运动和粘附、胞质分裂、囊泡转运、胞内力的产生以及发育过程中的形态发生。它的活性受轻链和可能的重链磷酸化作用以及与蛋白质(例如Mts1)的缔合的调节。在与巨核细胞/血小板/白细胞疾病有关的几种综合征中观察到了NMHCA基因的突变。MYH9基因的突变会引起一系列带有中性粒细胞包涵体的巨血小板减少症,称为MYH9病。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
肌球蛋白重链9在血小板中进行表达,编码它的基因位于22号染色体上。
肌球蛋白重链9(MYH9)基因编码非肌肉肌球蛋白重链IIA。
Immunogen
与人非肌肉肌球蛋白IIA的1949-1960氨基酸对应的合成肽。
Physical form
含有1% BSA及15 mM叠氮化钠的 0.01 M磷酸盐缓冲液(pH 7.4)溶液。
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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